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c-MYC 抗体 (pSer62)

Name: c-MYC 抗体 (pSer62)
SKU: ABIN3201011
Availability: OutOfStock

MYC 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 33A12E10 unconjugated

Western Blotting (WB) image for anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody (ABIN3201011)

Immunofluorescence (IF) image for anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody (ABIN3201011)

2 images

(2 references)

产品编号 ABIN3201011

发货至: 中国

Datasheet as PDF

抗原 See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
抗原表位
55

44

42

40

24

21

19

16

15

11

11

11

10

7

7

6

6

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer62
适用
372

170

123

15

14

13

13

13

9

9

8

6

6

6

5

4

3

3

2

2

2

1

1

1

1

1
人
宿主
295

96

7

3

2

1
小鼠
Compatible Secondaries
克隆类型
288

115
单克隆
标记
193

32

27

26

10

9

9

9

9

9

9

7

5

5

5

5

5

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
This c-MYC antibody is un-conjugated
应用范围
303

142

96

83

79

64

58

28

26

17

14

13

12

11

7

4

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

交叉反应（详细）

Expected to react with mouse, rat from the sequence identity.

纯化方法

Purified

免疫原

Synthetic peptide containing pSer62 of cMyc

克隆位点

33A12E10

亚型

IgG2b kappa

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anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
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anti-Myc Proto-Oncogene protein (MYC) antibody
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anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
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anti-Myc Proto-Oncogene protein (MYC) antibody
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应用备注

1. Western blotting: ~1 g/mL

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS, 50 % glycerol

储存液

Azide free

储存条件

-20 °C
Khanna, Böckelman, Hemmes, Junttila, Wiksten, Lundin, Junnila, Murphy, Evan, Haglund, Westermarck, Ristimäki: "MYC-dependent regulation and prognostic role of CIP2A in gastric cancer." in: Journal of the National Cancer Institute, Vol. 101, Issue 11, pp. 793-805, (2009) (PubMed).

Junttila, Puustinen, Niemelä, Ahola, Arnold, Böttzauw, Ala-aho, Nielsen, Ivaska, Taya, Lu, Lin, Chan, Wang, Grènman, Kast, Kallunki, Sears, Kähäri, Westermarck: "CIP2A inhibits PP2A in human malignancies." in: Cell, Vol. 130, Issue 1, pp. 51-62, (2007) (PubMed).
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

C-Myc (MYC 产品)

别名

MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody

背景

CMyc is a proto-oncogene, which is overexpressed in a wide range of human cancers. Myc gene encodes a transcription factor that regulates a great number of genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferase. It can also act as a transcriptional repressor. It regulates cell growth, apoptosis, differentiation and stem cell self-renewal. Previous studies on the phosphorylation of c-Myc have suggested functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK), cell proliferation and cell cycle regulation. Phosphorylation at Ser62 is required for Ras-induced stabilization and is prerequisite for phosphorylation at Thr58 for its degradation.

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect