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HRK 抗体 (Middle Region)

HRK 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318751
发货至: 中国
  • 抗原 See all HRK 抗体
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    抗原表位
    • 15
    • 13
    • 7
    • 2
    • 2
    • 1
    Middle Region
    适用
    • 29
    • 23
    • 18
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HRK antibody is un-conjugated
    应用范围
    • 18
    • 14
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects Harakiri (HRK), also known as DP5.
    纯化方法
    Purified
    免疫原
    15 amino acid peptide from near the centre of human HRK (NP_003797).
    亚型
    IgG
    Top Product
    Discover our top product HRK Primary Antibody
  • 应用备注
    Western Blot: 2 - 5g/mL, detects a band of approximately 13 kDa in mouse pancreas tissuelysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    别名
    Harakiri / HRK (HRK 产品)
    别名
    DP5 antibody, HARAKIRI antibody, AI838259 antibody, Bid3 antibody, harakiri antibody, Dp5 antibody, harakiri, BCL2 interacting protein antibody, harakiri, BCL2 interacting protein (contains only BH3 domain) antibody, HRK antibody, Hrk antibody
    背景
    HRK is a BH3 only protein of the Bcl-2 family, which promotes Bax dependent apoptosis. HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, in particular to growth factor deprivation. Aberrant methylation of HRK is frequently detected in primary colorectal cancers. Despite its predicted molecular weight, HRK often migrates at 12-15kD.Synonyms: Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, BID3, Neuronal death protein DP5
    基因ID
    8739
    NCBI登录号
    NP_003797
    UniProt
    O00198
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