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SERPINA5 抗体

SERPINA5 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317849
发货至: 中国
  • 抗原 See all SERPINA5 抗体
    SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
    适用
    • 51
    • 7
    • 5
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    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 7
    • 1
    • 1
    克隆类型
    • 47
    • 5
    多克隆
    标记
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
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    This SERPINA5 antibody is un-conjugated
    应用范围
    • 41
    • 25
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    PAI-3 antibody detects endogenous levels of PAI-3 protein.(region surrounding Leu291)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product SERPINA5 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
    别名
    SERPINA5 (SERPINA5 产品)
    别名
    4933415L04 antibody, PAI-3 antibody, Pci antibody, PAI3 antibody, PCI antibody, PCI-B antibody, PLANH3 antibody, PROCI antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, serpin family A member 5 antibody, serine (or cysteine) peptidase inhibitor, clade A, member 5 antibody, plasma serine protease inhibitor antibody, SPIA5 antibody, SERPINA5 antibody, Serpina5 antibody, LOC480424 antibody
    背景
    PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.Synonyms: Acrosomal serine protease inhibitor, PAI-3, PAI3, PCI, PLANH3, PROCI, Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, Protein C inhibitor, Serpin A5
    分子量
    approx. 42 kDa
    基因ID
    5104
    NCBI登录号
    NP_000615
    UniProt
    P05154
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