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SCN1A 抗体 (C-Term)

SCN1A 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044542
发货至: 中国
  • 抗原 See all SCN1A 抗体
    SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
    抗原表位
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1981-2009, C-Term
    适用
    • 25
    • 17
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 23
    • 3
    • 1
    克隆类型
    • 24
    • 3
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN1A antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Sodium channel protein type 1 subunit alpha(SCN1A) detection. Tested with WB in Human,Mouse,Rat.
    序列
    ACPPSYDRVT KPIVEKHEQE GKDEKAKGK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Sodium channel protein type 1 subunit alpha(SCN1A) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: sodium voltage-gated channel alpha subunit 1
    Protein Name: Sodium channel protein type 1 subunit alpha
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Scn1a (1981-2009aa ACPPSYDRVTKPIVEKHEQEGKDEKAKGK), identical to the related rat sequence.
    亚型
    IgG
    Top Product
    Discover our top product SCN1A Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
    别名
    SCN1A (SCN1A 产品)
    别名
    SCN9A antibody, SCN1A antibody, B230332M13 antibody, Nav1.1 antibody, EIEE6 antibody, FEB3 antibody, FEB3A antibody, FHM3 antibody, GEFSP2 antibody, HBSCI antibody, NAC1 antibody, SCN1 antibody, SMEI antibody, sodium voltage-gated channel alpha subunit 1 antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel, voltage-gated, type I, alpha antibody, SCN1A antibody, SCN9A antibody, Scn1a antibody
    背景
    Nav1.1, also known as the sodium channel, voltage-gated, type I, alpha subunit (SCN1A), is a protein which in humans is encoded by the SCN1A gene. Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

    Synonyms: brain sodium channel type I antibody|EIEE6 antibody|FEB3 antibody|FEB3A antibody|FHM3 antibody|GEFS+2 antibody|GEFSP2 antibody|HBSC I antibody|HBSCI antibody|NAC1 antibody|Nav 1.1 antibody|RBI antibody|SCN1 antibody|Scn1a antibody|SCN1A_HUMAN antibody|SMEI antibody| Sodium channel protein brain I alpha subunit antibody|Sodium channel protein brain I subunit alpha antibody|Sodium channel protein type 1 subunit alpha antibody|Sodium channel protein type I subunit alpha antibody|Sodium channel voltage gated type 1 alpha subunit antibody|Sodium channel voltage gated type I alpha polypeptide antibody|Voltage-gated sodium channel subunit alpha Nav1.1 antibody
    基因ID
    6323
    UniProt
    P35498
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