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CAMKK1 抗体 (N-Term)

CAMKK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044431
发货至: 中国
  • 抗原 See all CAMKK1 抗体
    CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))
    抗原表位
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-31, N-Term
    适用
    • 30
    • 16
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 23
    • 6
    • 1
    克隆类型
    • 26
    • 4
    多克隆
    标记
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CAMKK1 antibody is un-conjugated
    应用范围
    • 23
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    QDPRAELVDR VAAINVAHLE EA
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: calcium/calmodulin-dependent protein kinase kinase 1, alpha
    Protein Name: Calcium/calmodulin-dependent protein kinase kinase 1(CaM-KK 1/CaM-kinase kinase 1/CaMKK 1)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK(10-31aa QDPRAELVDRVAAINVAHLEEA), different from the related human sequence by three amino acids, and from the related rat sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CAMKK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))
    别名
    CAMKK1 (CAMKK1 产品)
    别名
    cam-kk antibody, cam-kk1 antibody, camkka antibody, zgc:113440 antibody, CAMKK1 antibody, CaM-KK antibody, CAMKKA antibody, AI846603 antibody, CaMKKalpha antibody, Camkk antibody, calcium/calmodulin-dependent protein kinase kinase 1 S homeolog antibody, calcium/calmodulin dependent protein kinase kinase 1 antibody, calcium/calmodulin-dependent protein kinase kinase 1, alpha a antibody, calcium/calmodulin-dependent protein kinase kinase 1 antibody, calcium/calmodulin-dependent protein kinase kinase 1, alpha antibody, camkk1.S antibody, CAMKK1 antibody, camkk1a antibody, camkk1 antibody, Camkk1 antibody
    背景
    CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The CAMKK1 gene is mapped to chromosome 17. The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.Camkk1binds calmodulin and activated Camk4 with a 6-fold increase in total activity and a 100-fold increase in Camk4 Ca(2+)-independent activity. Camkk1 catalyzed a 10-fold increase in the total activity of Camk1 and had no effect on Camk2. Cotransfection of COS-7 cells with Camkk1 and Camk4 resulted in a 14-fold increase in CRE-binding protein-dependent transcription compared with Camk4 alone, suggesting that Camkk1 enhances Camk4-mediated transcriptional regulation.

    Synonyms: Ca2+/calmodulin-dependent protein kinase kinase alpha antibody|Calcium/calmodulin dependent protein kinase kinase antibody|Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody|Calcium/calmodulin dependent protein kinase kinase 1 antibody|Calcium/calmodulin dependent protein kinase kinase alpha antibody|Calcium/calmodulin-dependent protein kinase kinase 1 antibody|Calcium/calmodulin-dependent protein kinase kinase alpha antibody|CaM kinase kinase alpha antibody|CaM-kinase IV kinase antibody|CaM-kinase kinase 1 antibody|CaM-kinase kinase alpha antibody|CaM-KK 1 antibody|CaM-KK alpha antibody|CaMKK 1 antibody|CaMKK alpha antibody|CAMKK alpha protein antibody|CaMKK antibody|CAMKK1 antibody|CAMKKA antibody|DKFZp761M0423 antibody|KKCC1_HUMAN antibody|MGC34095 antibody|OTTMUSP00000006419 antibody
    途径
    AMPK Signaling
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