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Caveolin-1 抗体 (C-Term)

CAV1 适用: 人, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044427
发货至: 中国
  • 抗原 See all Caveolin-1 (CAV1) 抗体
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    抗原表位
    • 15
    • 15
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 164-178, C-Term
    适用
    • 107
    • 63
    • 50
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 98
    • 12
    • 6
    • 2
    克隆类型
    • 93
    • 25
    多克隆
    标记
    • 82
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caveolin-1 antibody is un-conjugated
    应用范围
    • 92
    • 38
    • 27
    • 26
    • 26
    • 16
    • 16
    • 16
    • 11
    • 10
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit IgG polyclonal antibody for Caveolin-1(CAV1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    序列
    GKIFSNVRIN LQKEI
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Caveolin-1(CAV1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: caveolin 1, caveolae protein, 22 kDa
    Protein Name: Caveolin-1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Caveolin-1(164-178aa GKIFSNVRINLQKEI), different from the related rat and mouse sequences by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CAV1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Shi, Li, Jia, Ji, Song, Cheng, Wu, Song, Zhang, Zhu, Yang: "MicroRNA-199a-5p affects porcine preadipocyte proliferation and differentiation." in: International journal of molecular sciences, Vol. 15, Issue 5, pp. 8526-38, (2015) (PubMed).

    Wang, Zhao, Wu, He, Qu, Zhao, Zhao, Li, Wang: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).

  • 抗原
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    别名
    CAV1 (CAV1 产品)
    别名
    fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody
    背景
    CAV1, Caveolin-1, is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene.

    Synonyms: CAV 1 antibody|CAV antibody|CAV1 antibody|CAV1_HUMAN antibody|caveolae protein, 22 kD antibody|caveolin 1 alpha isoform antibody|caveolin 1 beta isoform antibody|Caveolin 1 caveolae protein 22 kDa antibody|Caveolin-1 antibody|Caveolin1 antibody|cell growth-inhibiting protein 32 antibody|MSTP085 antibody|OTTHUMP00000025031 antibody|VIP 21 antibody|VIP21 antibody
    UniProt
    Q03135
    途径
    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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