XIAP 抗体 (N-Term)
(4 references)-
- 抗原 See all XIAP 抗体
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
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抗原表位
- AA 14-34, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XIAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- ADINKEEEFV EEFNRLKTFA N
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: X-linked inhibitor of apoptosis
Protein Name: E3 ubiquitin-protein ligase XIAP - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human XIAP(14-34aa ADINKEEEFVEEFNRLKTFAN), different from the related mouse sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product XIAP Primary Antibody
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anti-X-Linked Inhibitor of Apoptosis (XIAP) (pSer87) antibody
XIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (C-Term) antibodyKO Validated XIAP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 201-330) antibodyXIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 51-150) antibodyXIAP 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (N-Term) antibodyXIAP 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-268) antibodyXIAP 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4C12G10 unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-30) antibodyXIAP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." in: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).
: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).
: "Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1." in: Biochemical and biophysical research communications, Vol. 434, Issue 4, pp. 809-14, (2013) (PubMed).
: "Exogenous ARC down-regulates caspase-3 expression and inhibits apoptosis of broiler chicken cardiomyocytes exposed to hydrogen peroxide." in: Avian pathology : journal of the W.V.P.A, Vol. 42, Issue 1, pp. 32-7, (2013) (PubMed).
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: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." in: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).
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- 抗原
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- 别名
- XIAP (XIAP 产品)
- 别名
- API3 antibody, BIRC4 antibody, IAP-3 antibody, ILP1 antibody, MIHA antibody, XLP2 antibody, hIAP-3 antibody, hIAP3 antibody, api3 antibody, birc4 antibody, ilp1 antibody, miha antibody, xlp2 antibody, xxiap antibody, 1110015C02Rik antibody, Aipa antibody, Api3 antibody, Birc4 antibody, IAP3 antibody, ILP-1 antibody, mXIAP antibody, riap3 antibody, fb73d01 antibody, wu:fb73d01 antibody, zgc:91873 antibody, BIRC8 antibody, X-linked inhibitor of apoptosis antibody, X-linked inhibitor of apoptosis L homeolog antibody, XIAP antibody, xiap antibody, xiap.L antibody, Xiap antibody
- 背景
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BIRC4, baculoviral IAP repeat-containing protein 4 is also known as XIAP(X-linked inhibitor of apoptosis protein). The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Synonyms: AP 13 antibody|API3 antibody|Apoptosis Inhibitor 3 antibody|Baculoviral IAP repeat containing 4 antibody|Baculoviral IAP Repeat Containing Protein 4 antibody|Baculoviral IAP repeat-containing protein 4 antibody|BIRC 4 antibody|BIRC4 antibody|E3 ubiquitin-protein ligase XIAP antibody|hIAP-3 antibody|hIAP3 antibody|HILP antibody|IAP 3 antibody|IAP like protein antibody|IAP-3 antibody|IAP-like protein antibody|IAP3 antibody|ILP 1 antibody|ILP antibody|ILP1 antibody|Inhibitor of apoptosis protein 3 antibody|Inhibitor of Apoptosis X Linked antibody|Mammalian IAP Homologue A antibody|MIHA antibody|X linked IAP antibody|X linked inhibitor of apoptosis antibody|X linked inhibitor of apoptosis protein antibody|X-linked IAP antibody|X-linked inhibitor of apoptosis protein antibody|Xiap antibody|XIAP_HUMAN antibody|XLP2 antibody - UniProt
- P98170
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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