CAMKK2 抗体 (Middle Region)
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- 抗原 See all CAMKK2 抗体
- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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抗原表位
- AA 180-194, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAMKK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 2(CAMKK2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- KLAYNENDNT YYAMK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 2(CAMKK2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Protein Name: Calcium/calmodulin-dependent protein kinase kinase 2(CaM-KK 2/CaM-kinase kinase 2/CaMKK 2) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CAMKK2(180-194aa KLAYNENDNTYYAMK), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product CAMKK2 Primary Antibody
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anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-130) antibody
CAMKK2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-541) antibodyCAMKK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 2-137) antibodyCAMKK2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (C-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyKO Validated CAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512), (C-Term) antibodyCAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12560 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, Cow, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 43-71), (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) antibodyCAMKK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 239CT7-5-3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512) antibodyCAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Predicted Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
- 别名
- CAMKK2 (CAMKK2 产品)
- 别名
- CAMKK antibody, CAMKKB antibody, 6330570N16Rik antibody, AW061083 antibody, mKIAA0787 antibody, camk2b antibody, fj90d04 antibody, wu:fj90d04 antibody, si:dkey-174n20.2 antibody, CAMKK2 antibody, calcium/calmodulin dependent protein kinase kinase 2 antibody, calcium/calmodulin-dependent protein kinase kinase 2, beta antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase kinase 2 antibody, CAMKK2 antibody, Camkk2 antibody, camk2b1 antibody, CAMK2B antibody, camkk2 antibody
- 背景
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CAMKK2, Calcium/calmodulin-dependent protein kinase kinase 2, is an enzyme that in humans is encoded by the CAMKK2 gene. The product of this gene belongs to the serine/threonine-specific protein kinase family, and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus. It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs, through reduction in downstream signalling pathways and mu opioid receptor downregulation. Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss.
Synonyms: Calcium/calmodulin dependent protein kinase beta antibody|Calcium/calmodulin dependent protein kinase kinase 2 antibody|Calcium/calmodulin dependent protein kinase kinase 2 beta antibody|Calcium/calmodulin dependent protein kinase kinase beta antibody|Calcium/calmodulin-dependent protein kinase kinase 2 antibody|Calcium/calmodulin-dependent protein kinase kinase beta antibody|CaM kinase kinase beta antibody|CaM KK beta antibody|CaM-kinase kinase 2 antibody|CaM-kinase kinase beta antibody|CaM-KK 2 antibody|CaM-KK beta antibody|CAMKK 2 antibody|CAMKK antibody|CaMKK beta antibody|CAMKK beta protein antibody|Camkk2 antibody|CAMKKB antibody|KKCC2_HUMAN antibody - 途径
- AMPK Signaling
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