TNFRSF1A 抗体 (Middle Region)
(4 references)-
- 抗原 See all TNFRSF1A 抗体
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
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抗原表位
- AA 195-211, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) detection. Tested with WB, IHC-P in Human.
- 序列
- CLPQIENVKG TEDSGTT
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) detection. Tested with WB, IHC-P in Human.
Gene Name: tumor necrosis factor receptor superfamily, member 1A
Protein Name: Tumor necrosis factor receptor superfamily member 1A - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TNF Receptor I(195-211aa CLPQIENVKGTEDSGTT) .
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF1A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 248-428) antibody
TNFRSF1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) antibodyTNFRSF1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibodyTNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (HRP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (FITC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Alkaline Phosphatase (AP))TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Biotin)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PE)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (APC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PerCP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir." in: International journal of molecular sciences, Vol. 17, Issue 6, (2017) (PubMed).
: "Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization." in: Scientific reports, Vol. 4, pp. 4990, (2015) (PubMed).
: "TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling." in: Pain, Vol. 155, Issue 12, pp. 2618-29, (2015) (PubMed).
: "Soluble tumor necrosis factor receptor mediates cell proliferation on lipopolysaccharide-stimulated cultured human decidual stromal cells." in: International journal of molecular sciences, Vol. 10, Issue 5, pp. 2010-8, (2014) (PubMed).
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: "Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir." in: International journal of molecular sciences, Vol. 17, Issue 6, (2017) (PubMed).
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- 抗原
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- 别名
- TNFRSF1A (TNFRSF1A 产品)
- 别名
- CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
- 背景
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Tumor necrosis factor receptor 1(TNFR1), a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. Its gene is located on 12p13.2. The coding region and the 3-prime untranslated region of TNFR1 are distributed over 10 exons. There are 2 different proteins that serve as major receptors for TNF-alpha, one associated with myeloid cells and one associated with epithelial cells. Additionally, TNFR1 associates with the MADD protein through a death domain-death domain interaction. MADD provides a physical link between TNFR1 and the induction of mitogen-activated protein(MAP) kinase(e.g., ERK2) activation and arachidonic acid release. TNFR1-induced apoptosis involves 2 sequential signaling complexes. Complex I, the initial plasma membrane-bound complex, consists of TNFR1, the adaptor TRADD, the kinase RIP1, and TRAF2 and rapidly signals activation of NF-kappa-B. In a second step, TRADD and RIP1 associate with FADD and caspase-8, forming a cytoplasmic complex, complex II.
Synonyms: CD120a antibody|FPF antibody|MGC19588 antibody|p55 antibody|p55 R antibody|P55R antibody|p60 antibody|TBP 1 antibody|TBP1 antibody|TBPI antibody|TNF R antibody|TNF R I antibody|TNF R55 antibody|TNF-R1 antibody|TNF-RI antibody|TNFAR antibody|TNFR 55 antibody|TNFR 60 antibody|TNFR antibody|TNFR-I antibody|TNFR1 antibody|TNFR55 antibody|TNFR60 antibody|TNFRI antibody|TNFRSF1A antibody|TNR1A_HUMAN antibody|Tumor necrosis factor alpha receptor antibody|Tumor necrosis factor binding protein 1 antibody|Tumor necrosis factor receptor 1 antibody|Tumor necrosis factor receptor superfamily member 1A antibody|Tumor necrosis factor receptor type 1 antibody|Tumor necrosis factor receptor type I antibody|Tumor necrosis factor-binding protein 1 antibody - UniProt
- P19438
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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