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Arrestin 3 抗体 (C-Term)

ARRB2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044208
发货至: 中国
  • 抗原 See all Arrestin 3 (ARRB2) 抗体
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    抗原表位
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 395-409, C-Term
    适用
    • 48
    • 27
    • 26
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 40
    • 5
    • 3
    克隆类型
    • 43
    • 5
    多克隆
    标记
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Arrestin 3 antibody is un-conjugated
    应用范围
    • 40
    • 18
    • 16
    • 13
    • 13
    • 12
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Beta-arrestin-2(ARRB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    RLKGMKDDDY DDQLC
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Beta-arrestin-2(ARRB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: arrestin beta-2
    Protein Name: Beta-arrestin-2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Beta Arrestin 2(395-409aa RLKGMKDDDYDDQLC), different from the related rat and mouse sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ARRB2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for ARRB2 is approximately 5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    别名
    ARRB2 (ARRB2 产品)
    别名
    ARRB2 antibody, arb2 antibody, arr2 antibody, arrestin antibody, barr2 antibody, betaarr2 antibody, ARB2 antibody, ARR2 antibody, BARR2 antibody, BARRES antibody, AI326910 antibody, AW122872 antibody, arrb2 antibody, zgc:64007 antibody, arrestin beta 2 antibody, arrestin, beta 2 antibody, arrestin beta 2 L homeolog antibody, arrestin, beta 2b antibody, ARRB2 antibody, arrb2 antibody, Arrb2 antibody, arrb2.L antibody, arrb2b antibody
    背景
    ARRB2(arrestin beta-2), also known as Beta-arrestin-2, BARR2, ARB2, DKFZp686L0365, arrestin 3, is an intracellularprotein that in humans is encoded by the ARRB2 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Beta-arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors.

    Synonyms: ARB 2 antibody|ARB2 antibody|ARR 2 antibody|ARR2 antibody|ARRB 2 antibody|ARRB2 antibody|ARRB2_HUMAN antibody|Arrestin 3 antibody|Arrestin beta 2 antibody|Arrestin beta-2 antibody|BARR2 antibody|Beta-arrestin-2 antibody|DKFZp686L0365 antibody|HGNC:712 antibody
    UniProt
    P32121
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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