电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NOL3 抗体 (Middle Region)

NOL3 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044179
发货至: 中国
  • 抗原 See all NOL3 抗体
    NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
    抗原表位
    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 91-106, Middle Region
    适用
    • 31
    • 27
    • 8
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 45
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOL3 antibody is un-conjugated
    应用范围
    • 21
    • 13
    • 13
    • 12
    • 10
    • 9
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Nucleolar protein 3(NOL3) detection. Tested with WB in Human,Mouse,Rat.
    序列
    WDWQHVGPGY RDRSYD
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Nucleolar protein 3(NOL3) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: nucleolar protein 3(apoptosis repressor with CARD doma)
    Protein Name: Nucleolar protein 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human Apoptosis repressor with CARD(91-106aa WDWQHVGPGYRDRSYD), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product NOL3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
    别名
    NOL3 (NOL3 产品)
    别名
    ARC antibody, FCM antibody, MYP antibody, NOP antibody, NOP30 antibody, B430311C09Rik antibody, MYC antibody, Nop30 antibody, Arc antibody, nucleolar protein 3 antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, NOL3 antibody, Nol3 antibody
    背景
    NOL3(Nucleolar protein 3), also known as ARC, NOP30, CARD2 and MYP, is a protein that in humans is encoded by the NOL3 gene. NOL3 has been shown to interact with SFRS9 and Caspase 8. By genomic sequence analysis, Stoss et al.(1999) determined that the NOL3 gene, which encodes NOP30 and MYP and which they called NOP, is composed of 4 exons. The alternative 5-prime splice site that generates the 2 isoforms is located in exon 2. It is reported that expression of the ARC cDNA encoding the smaller transcript inhibited apoptosis in a dose-dependent manner when coexpressed with CASP8 but not when coexpressed with CASP9. ARC also inhibited apoptosis induced by stimulation of CD95/FAS, tumor necrosis factor receptor-1, and TRAMP/death receptor-3. Enzymatic analysis showed that ARC inhibits the enzymatic activity of CASP8. Immunoprecipitation and immunoblot analysis indicated that ARC interacts with CASP2 and CASP8 through its N-terminal death effector domain but does not interact with CASP1, CASP3, or CASP9.

    Synonyms: Apoptosis repressor with CARD antibody|ARC antibody|Muscle enriched cytoplasmic protein antibody|Muscle-enriched cytoplasmic protein antibody|MYC antibody|MYP antibody|Nol3 antibody|NOL3_HUMAN antibody|NOP antibody|Nop30 antibody|Nucleolar protein 3(apoptosis repressor with CARD domain) antibody|Nucleolar protein 3 antibody|Nucleolar protein of 30 kDa antibody
    UniProt
    O60936
You are here:
客服