(4 references)-
- 抗原 See all CXCL1 抗体
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
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抗原表位
- AA 99-107, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Growth-regulated alpha protein(CXCL1) detection. Tested with WB in Human.
- 序列
- KMLNSDKSN
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Growth-regulated alpha protein(CXCL1) detection. Tested with WB in Human.
Gene Name: chemokine(C-X-C motif) ligand 1(melanoma growth stimulating activity, alpha)
Protein Name: Growth-regulated alpha protein - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GRO alpha(99-107aa KMLNSDKSN).
- 亚型
- IgG
- Top Product
- Discover our top product CXCL1 Primary Antibody
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anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (Internal Region) antibody
CXCL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 51-107) antibodyCXCL1 适用: 人, 小鼠 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 25-96) antibodyCXCL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 35-107) antibodyCXCL1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 25-96) antibodyCXCL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) antibodyCXCL1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 36-107) antibodyCXCL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) antibody (Biotin)CXCL1 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) antibody (Biotin)CXCL1 适用: 大鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (AA 1-107) antibodyCXCL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice." in: Journal of neuroinflammation, Vol. 11, pp. 38, (2014) (PubMed).
: "Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice." in: Brain : a journal of neurology, Vol. 137, Issue Pt 8, pp. 2193-209, (2014) (PubMed).
: "Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2." in: Experimental neurology, Vol. 261, pp. 328-36, (2014) (PubMed).
: "Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons." in: Pain, Vol. 154, Issue 10, pp. 2185-97, (2013) (PubMed).
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: "NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice." in: Journal of neuroinflammation, Vol. 11, pp. 38, (2014) (PubMed).
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- 抗原
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
- 别名
- CXCL1 (CXCL1 产品)
- 别名
- FSP antibody, GRO1 antibody, GROa antibody, MGSA antibody, MGSA-a antibody, NAP-3 antibody, SCYB1 antibody, CINC-1 antibody, Gro1 antibody, CXCL1 antibody, Sdf1 antibody, Fsp antibody, KC antibody, Mgsa antibody, N51 antibody, Scyb1 antibody, gro antibody, GRO antibody, Gro antibody, C-X-C motif chemokine ligand 1 antibody, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody, C-X-C motif chemokine ligand 12 antibody, chemokine (C-X-C motif) ligand 1 antibody, CXCL1 antibody, Cxcl1 antibody, Cxcl12 antibody, GRO1 antibody
- 背景
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CXCL1(Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROalpha, KC, Neutrophil-activating protein 3(NAP-3) and melanoma growth stimulating activity, alpha(MSGA-alpha). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation,wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated.
Synonyms: C-X-C motif chemokine 1 antibody|Chemokine(C X C motif) ligand 1 antibody|Chemokine(C-X-C motif) ligand 1(melanoma growth stimulating activity, alpha) antibody|chemokine(C-X-C motif) ligand 1 antibody|Chemokine ligand 1 antibody|CINC-1 antibody|Cxcl 1 antibody|Cxcl1 antibody|Cytokine-induced neutrophil chemoattractant 1 antibody|Fibroblast secretory protein antibody|Fsp antibody|Gro 1 antibody|Gro A antibody|GRO alpha antibody|GRO antibody|GRO protein, alpha antibody|GRO-alpha(1-73) antibody|GRO-alpha(6-73) antibody|Gro1 antibody|GRO1 oncogene(melanoma growth stimulating activity, alpha) antibody|GRO1 oncogene(melanoma growth-stimulating activity) antibody|Gro1 oncogene antibody|GroA antibody|GROA_HUMAN antibody|Growth regulated protein alpha antibody|Growth regulated protein GRO antibody|KC antibody|KC chemokine, mouse, homolog of antibody|Melanoma growth stimulatory activity alpha antibody|Melanoma growth stimulatory activity antibody|Melanoma growth stimulatory activity, alpha antibody|MGSA a antibody|MGSA alpha antibody|MGSA antibody|MGSA-a antibody|N51 antibody|NAP 3 antibody|NAP-3 antibody|NAP3 antibody|Neutrophil activating protein 3 antibody|Neutrophil-activating protein 3 antibody|Platelet-derived growth factor-inducible protein KC antibody|Scyb 1 antibody|SCYB1 antibody|Secretory protein N51 antibody|Small inducible cytokine subfamily B, member 1 antibody - UniProt
- P09341
- 途径
- Autophagy
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