电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TJP2 抗体 (C-Term)

TJP2 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044036
发货至: 中国
  • 抗原 See all TJP2 抗体
    TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
    抗原表位
    • 15
    • 14
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1149-1167, C-Term
    适用
    • 68
    • 27
    • 24
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 63
    • 4
    • 3
    克隆类型
    • 67
    • 3
    多克隆
    标记
    • 38
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TJP2 antibody is un-conjugated
    应用范围
    • 59
    • 32
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Tight junction protein ZO-2(TJP2) detection. Tested with WB, IHC-P in Mouse,Rat.
    序列
    AHSKRGYYSQ PSRYRDTEL
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Tight junction protein ZO-2(TJP2) detection. Tested with WB, IHC-P in Mouse,Rat.
    Gene Name: tight junction protein 2
    Protein Name: Tight junction protein ZO-2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse TJP2(1149-1167aa AHSKRGYYSQPSRYRDTEL), identical to the related rat sequence.
    亚型
    IgG
    Top Product
    Discover our top product TJP2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, The detection limit for TJP2 is approximately 2.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
    别名
    TJP2 (TJP2 产品)
    别名
    C9DUPq21.11 antibody, DFNA51 antibody, DUP9q21.11 antibody, X104 antibody, ZO2 antibody, ZO-2 antibody, zo2 antibody, tjp2 antibody, x104 antibody, zo-2 antibody, wu:fb62b09 antibody, zgc:92094 antibody, tight junction protein 2 antibody, tight junction protein 2 L homeolog antibody, tight junction protein 2b (zona occludens 2) antibody, TJP2 antibody, Tjp2 antibody, tjp2.L antibody, tjp2b antibody
    背景
    TJP2(Tight Junction Protein 2), also known as Zona Occludens 2 or ZO2, is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins(TJPs) belong to a family of membrane-associated guanylate kinase(MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al.(1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. TJP2 lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction. Using in vitro assays and immunoprecipitation studies, Itoh et al.(1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50 % of the level at birth(P0).

    Synonyms: Friedreich ataxia region gene X104(tight junction protein ZO-2) antibody|MGC26306 antibody|Tight junction protein 2 antibody|Tight junction protein ZO 2 antibody|Tight junction protein ZO-2 antibody|TJP2 antibody|X104 antibody|ZO 2 antibody|ZO-2 antibody|ZO2 antibody|ZO2_HUMAN antibody|Zona occludens protein 2 antibody|Zonula occludens protein 2 antibody
    UniProt
    Q9Z0U1
You are here:
客服