Aquaporin 4 抗体 (C-Term)
(4 references)-
- 抗原 See all Aquaporin 4 (AQP4) 抗体
- Aquaporin 4 (AQP4)
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抗原表位
- AA 258-274, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aquaporin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Aquaporin-4(AQP4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- FKRRFKEAFS KAAQQTK
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Aquaporin-4(AQP4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: aquaporin 4
Protein Name: Aquaporin-4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4(258-274aa FKRRFKEAFSKAAQQTK), different from the related rat and mouse sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AQP4 Primary Antibody
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anti-Aquaporin 4 (AQP4) (AA 271-323) antibody
AQP4 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 178-317) antibodyAQP4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Aquaporin 4 (AQP4) (AA 244-323) antibodyAQP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 295-323), (C-Term) antibodyAQP4 适用: 人, 大鼠, 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 253-323) antibodyAQP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) antibodyAQP4 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) antibodyAQP4 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) antibodyMicroarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB430199 unconjugated
anti-Aquaporin 4 (AQP4) antibodyMicroarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB287702 unconjugated
anti-Aquaporin 4 (AQP4) antibodyAQP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for AQP4 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure." in: International journal of molecular sciences, Vol. 19, Issue 1, (2018) (PubMed).
: "Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema." in: Molecular medicine reports, Vol. 12, Issue 4, pp. 5625-32, (2016) (PubMed).
: "Neuroprotective effects of total steroid saponins on cerebral ischemia injuries in an animal model of focal ischemia/reperfusion." in: Planta medica, Vol. 80, Issue 8-9, pp. 637-44, (2015) (PubMed).
: "Ulinastatin attenuates cerebral ischemia-reperfusion injury in rats." in: International journal of clinical and experimental medicine, Vol. 7, Issue 5, pp. 1483-9, (2014) (PubMed).
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: "Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure." in: International journal of molecular sciences, Vol. 19, Issue 1, (2018) (PubMed).
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- 抗原
- Aquaporin 4 (AQP4)
- 别名
- AQP4 (AQP4 产品)
- 别名
- zgc:100922 antibody, si:ch211-192k9.1 antibody, AQP4 antibody, LOC100232616 antibody, HMIWC2 antibody, MIWC antibody, WCH4 antibody, AQP-4 antibody, AQP4.M23 antibody, MIWC2 antibody, Miwc antibody, aquaporin-4 antibody, aquaporin 4 antibody, aquaporin 4 L homeolog antibody, aqp4 antibody, AQP4 antibody, aqp4.L antibody, Aqp4 antibody
- 背景
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AQP4(Aquaporin 4), also known as MERCURIAL-INSENSITIVE WATER CHANNEL, MIWC, is protein which in humans is encoded by the AQP4 gene. The aquaporins are a family of water-selective membrane channels found in animals, plants, and microorganisms. AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. By fluorescence in situ hybridization, Lu et al.(1996) determined that the AQP4 gene maps to 18q11.2-q12.1. By interspecific backcross analysis, Turtzo et al.(1997) mapped the mouse Aqp4 gene to the proximal region of chromosome 18. Analyzing the expression of AQP4 in mammalian skeletal muscle, Frigeri et al.(1998) found that, in immunohistochemical experiments, affinity-purified AQP4 antibodies stained selectively the sarcolemma of fast-twitch fibers. Immunocytochemistry revealed strong AQP4 water channel expression in Muller cells in mouse retina and in fibrous astrocytes in optic nerve.
Synonyms: AQP 4 antibody|AQP-4 antibody|AQP4 antibody|AQP4_HUMAN antibody|Aquaporin type 4 antibody|Aquaporin-4 antibody|Aquaporin4 antibody|HMIWC 2 antibody|HMIWC2 antibody|Mercurial insensitive water channel antibody|Mercurial-insensitive water channel antibody|MGC22454 antibody|MIWC antibody|WCH 4 antibody|WCH4 antibody - UniProt
- P55087
- 途径
- Sensory Perception of Sound
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