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SLC6A4 抗体 (N-Term)

SLC6A4 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043931
发货至: 中国
  • 抗原 See all SLC6A4 抗体
    SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))
    抗原表位
    • 15
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-85, N-Term
    适用
    • 39
    • 29
    • 25
    • 15
    • 1
    人, 大鼠
    宿主
    • 34
    • 10
    • 2
    克隆类型
    • 34
    • 11
    • 1
    多克隆
    标记
    • 30
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC6A4 antibody is un-conjugated
    应用范围
    • 35
    • 14
    • 13
    • 10
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.
    序列
    DDTRHSIPAT TTTLVAELHQ GERETWGKK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
    Protein Name: Sodium-dependent serotonin transporter
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A4 (57-85aa DDTRHSIPATTTTLVAELHQGERETWGKK), different from the related mouse and rat sequences by six amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SLC6A4 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC6A4 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))
    别名
    SLC6A4 (SLC6A4 产品)
    别名
    5-HTT antibody, 5-HTTLPR antibody, 5HTT antibody, HTT antibody, OCD1 antibody, SERT antibody, SERT1 antibody, hSERT antibody, AI323329 antibody, Htt antibody, Sert antibody, CG4545 antibody, DmSERT antibody, DmSerT antibody, Dmel\\CG4545 antibody, dSERT antibody, dSERT1 antibody, dSerT antibody, dSert antibody, dsert antibody, SLC6A4 antibody, solute carrier family 6 member 4 antibody, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody, Serotonin transporter antibody, huntingtin antibody, solute carrier family 6 (neurotransmitter transporter), member 4b antibody, solute carrier family 6 (neurotransmitter transporter), member 4a antibody, SLC6A4 antibody, Slc6a4 antibody, SerT antibody, LOC100540532 antibody, slc6a4 antibody, slc6a4b antibody, slc6a4a antibody
    背景
    SLC6A4 (Solute carrier family 6, member 4), also known as SERT (serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium: neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.

    Synonyms: 5 HTT antibody|5 HTTLPR antibody|5 hydroxytryptamine (serotonin) transporter antibody|5 hydroxytryptamine transporter antibody|5HT transporter antibody|5HTT antibody|hSERT antibody|HTT antibody|Na+/Cl- dependent serotonin transporter antibody|OCD1 antibody| SC6A4_HUMAN antibody|Serotonin transporter 1 antibody|SERT antibody|SERT1 antibody|SLC6A4 antibody|Sodium dependent serotonin transporter antibody|Sodium-dependent serotonin transporter antibody|Solute carrier family 6 (neurotransmitter transporter) member 4 antibody|solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody|Solute carrier family 6 member 4 antibody
    基因ID
    6532
    UniProt
    P31645
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