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Glutamate Receptor 1 抗体 (AA 19-360)

GLUR1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043837
发货至: 中国
  • 抗原 See all Glutamate Receptor 1 (GLUR1) 抗体
    Glutamate Receptor 1 (GLUR1)
    抗原表位
    • 17
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    • 5
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    • 2
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    • 1
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    • 1
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    • 1
    AA 19-360
    适用
    • 110
    • 109
    • 93
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 120
    • 25
    • 1
    克隆类型
    • 109
    • 37
    多克隆
    标记
    • 71
    • 8
    • 6
    • 6
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    • 3
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    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glutamate Receptor 1 antibody is un-conjugated
    应用范围
    • 98
    • 40
    • 40
    • 38
    • 37
    • 27
    • 15
    • 15
    • 13
    • 5
    • 4
    • 2
    • 1
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: glutamate receptor, ionotropic, AMPA 1
    Protein Name: Glutamate receptor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.
    亚型
    IgG
    Top Product
    Discover our top product GLUR1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GRIA1 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Liu, Mei, Li, Roboti, Pang, Ying, Gao, Lowe, Bao: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).

  • 抗原
    Glutamate Receptor 1 (GLUR1)
    别名
    GRIA1 (GLUR1 产品)
    别名
    GLUH1 antibody, GLUR1 antibody, GLURA antibody, GluA1 antibody, HBGR1 antibody, gluR-A antibody, 2900051M01Rik antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody, gluR-K1 antibody, GRIA1 antibody, glur1 antibody, Gria1 antibody, glur1b antibody, gria1.2 antibody, sb:eu293 antibody, ZfGluR1a antibody, glur1a antibody, gria1.1 antibody, zfGRIA1[a] antibody, glutamate ionotropic receptor AMPA type subunit 1 antibody, glutamate receptor, ionotropic, AMPA1 (alpha 1) antibody, glutamate receptor, ionotropic, AMPA 1 antibody, glutamate receptor, ionotropic, AMPA 1 L homeolog antibody, GluR1 protein antibody, Glutamate receptor 1 antibody, glutamate receptor, ionotropic, AMPA 1b antibody, glutamate receptor, ionotropic, AMPA 1a antibody, GRIA1 antibody, Gria1 antibody, gria1 antibody, gria1.L antibody, glur1 antibody, glr-1 antibody, gria1b antibody, gria1a antibody
    背景
    GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

    Synonyms: GLUR 1 antibody|GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH 1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody
    基因ID
    2890
    UniProt
    P42261
    途径
    PI3K-Akt Signaling
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