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MAFA 抗体 (Middle Region)

MAFA 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043609
发货至: 中国
  • 抗原 See all MAFA 抗体
    MAFA (Transcription Factor MafA (MAFA))
    抗原表位
    • 12
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 136-167, Middle Region
    适用
    • 49
    • 32
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 50
    • 3
    克隆类型
    • 50
    • 3
    多克隆
    标记
    • 29
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAFA antibody is un-conjugated
    应用范围
    • 49
    • 20
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Transcription factor MafA(MAFA) detection. Tested with WB in Human,Rat.
    序列
    EDAVEALIGS GHHGAHHGAH HPAAAAAYEA FR
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Transcription factor MafA(MAFA) detection. Tested with WB in Human,Rat.
    Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
    Protein Name: Transcription factor MafA
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human MAFA(136-167aa EDAVEALIGSGHHGAHHGAHHPAAAAAYEAFR), identical to the related mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product MAFA Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for MAFA is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    MAFA (Transcription Factor MafA (MAFA))
    别名
    MAFA (MAFA 产品)
    别名
    RIPE3b1 antibody, hMafA antibody, RGD1562627 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, SMaf1 antibody, mafl antibody, L-MAF antibody, MAFL antibody, Maf antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antibody, MAF bZIP transcription factor A antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antibody, monocyte to macrophage differentiation-associated antibody, Mafa antibody, MAFA antibody, Klrg1 antibody, mafa antibody, mafaa antibody, Mmd antibody
    背景
    MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA plays a key role in coordinating and controlling the level of insulin gene expression in islet beta cells. It is located in 8q24.3. The intracellular domain of MAFA contains a single immunoreceptor tyrosine-based inhibitory motif (ITIM), which classifies MAFA as a member of an inhibitory receptor superfamily. The inhibitory capacity of MAFA is best defined in mast cells, where MAFA keeps in check the antigen-induced (i.e. Fc epsilon RI-induced) secretion ofinflammatory mediators.

    Synonyms: HMafA antibody|Mafa antibody|MAFA_HUMAN antibody|Pancreatic beta cell specific transcriptional activator antibody|Pancreatic beta-cell-specific transcriptional activator antibody|RIPE3b1 antibody|Transcription factor MafA antibody|Transcription factor RIPE3b1 antibody|v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) antibody|v maf musculoaponeurotic fibrosarcoma oncogene homolog A antibody|V-maf musculoaponeurotic fibrosarcoma oncogene homolog A antibody
    基因ID
    389692
    途径
    Hormone Transport
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