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- 抗原 See all APH1A 抗体
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
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抗原表位
- AA 236-265, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APH1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Gamma-secretase subunit APH-1A(APH1A) detection. Tested with WB in Human,Mouse.
- 序列
- LRSIQRSLLC RRQEDSRVMV YSALRIPPED
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Gamma-secretase subunit APH-1A(APH1A) detection. Tested with WB in Human,Mouse.
Gene Name: APH1A gamma secretase subunit
Protein Name: Gamma-secretase subunit APH-1A - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human APH1a (236-265aa LRSIQRSLLCRRQEDSRVMVYSALRIPPED), different from the related mouse sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product APH1A Primary Antibody
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anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 71-170) antibody
APH1A 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Internal Region) antibodyVerified APH1A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (C-Term) antibodyAPH1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 90-118) antibodyAPH1A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) antibodyAPH1A 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 80-130) antibodyAPH1A 适用: 人, Cow, 犬, 马, 猴, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 77-109), (N-Term) antibodyAPH1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4994 unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Middle Region) antibodyAPH1A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for APH1a is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
- 别名
- APH1A (APH1A 产品)
- 别名
- 6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
- 背景
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APH1a encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants.
Synonyms: 6530402N02Rik antibody|AL138795.3 antibody|Anterior Pharynx Defective 1 antibody|Anterior pharynx defective 1 homolog A antibody|APH 1A antibody|Aph 1alpha antibody|APH-1a antibody| Aph-1alpha antibody|Aph1a antibody|APH1A gamma secretase subunit antibody|APH1A_HUMAN antibody|CGI 78 antibody|CGI78 antibody|Gamma secretase subunit APH 1A antibody|Gamma Secretase Subunit APH1a antibody|Gamma-secretase subunit APH-1A antibody|Likely ortholog of C. elegans anterior pharynx defective 1A antibody|Presenilin Stabilization Factor antibody| Presenilin-stabilization factor antibody|PSF antibody|UNQ579/PRO1141 antibody - 基因ID
- 51107
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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