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- 抗原 See all FE65 (APBB1) 抗体
- FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
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抗原表位
- AA 295-613
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FE65 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Amyloid beta A4 precursor protein-binding family B member 1(APBB1) detection. Tested with WB in Human,Mouse.
- 交叉反应 （详细）
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Amyloid beta A4 precursor protein-binding family B member 1(APBB1) detection. Tested with WB in Human,Mouse.
Gene Name: amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Protein Name: Amyloid beta A4 precursor protein-binding family B member 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FE65 recombinant protein (Position: Q295-A613). Human FE65 shares 95%and 96% amino acid (aa) sequence identity with mouse and rat FE65, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product APBB1 Primary Antibody
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anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 21-56), (N-Term) antibody
APBB1 适用: 小鼠, 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 201-300) antibodyAPBB1 适用: 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 361-710) antibodyAPBB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 1-708) antibodyAPBB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (C-Term) antibodyAPBB1 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) antibodyAPBB1 适用: 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (pSer175) antibodyAPBB1 适用: 小鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (C-Term) antibodyVerified APBB1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 197-246) antibodyAPBB1 适用: 小鼠, 人, 大鼠, 兔, 犬, Cow, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1) (AA 359-708) antibodyAPBB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for FE65 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
- 别名
- APBB1 (APBB1 产品)
- 别名
- FE65 antibody, MGC:9072 antibody, RIR antibody, apbb1 antibody, MGC80654 antibody, Fe65 antibody, Rir antibody, amyloid beta precursor protein binding family B member 1 antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 antibody, APBB1 antibody, apbb1.L antibody, Apbb1 antibody
- 背景
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APBB1 is also known as RIR or FE65. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms: Adaptor protein FE65a2 antibody|Amyloid beta (A4) precursor protein binding family B member 1 antibody|Amyloid Beta A4 Precursor Protein Binding Family B antibody|Amyloid beta A4 precursor protein binding family B member 1 antibody|Amyloid beta A4 precursor protein-binding family B member 1 antibody|Amyloid beta precursor protein binding family B member 1 antibody|APBB 1 antibody|APBB1 antibody|APBB1_HUMAN antibody|FE 65 antibody|Fe65 protein antibody|Protein Fe65 antibody|RIR antibody|stat like protein antibody - 基因ID
- 322
- UniProt
- O00213
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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