电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MMP14 抗体 (C-Term)

MMP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043408
发货至: 中国
  • 抗原 See all MMP14 抗体
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    抗原表位
    • 14
    • 13
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 557-582, C-Term
    适用
    • 95
    • 34
    • 33
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 84
    • 11
    • 1
    克隆类型
    • 74
    • 22
    多克隆
    标记
    • 52
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MMP14 antibody is un-conjugated
    应用范围
    • 66
    • 47
    • 36
    • 18
    • 14
    • 11
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Matrix metalloproteinase-14(MMP14) detection. Tested with WB in Human.
    序列
    LAVFFFRRHG TPRRLLYCQR SLLDKV
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Matrix metalloproteinase-14(MMP14) detection. Tested with WB in Human.
    Gene Name: matrix metallopeptidase 14 (membrane-inserted)
    Protein Name: Matrix metalloproteinase-14
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human MMP14 (557-582aa LAVFFFRRHGTPRRLLYCQRSLLDKV), different from the related mouse and rat sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product MMP14 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MMP14 is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Tang, Pei, Yang, Wang, Wang, Gao, Li, Yang, Yang: "The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).

    Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

    Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." in: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

    Shi, Wang, Zhang, Li, Guo, Li, Chen: "Effect of lentivirus-mediated uPA silencing on the proliferation and apoptosis of chondrocytes and the expression of MMPs." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 111-6, (2015) (PubMed).

    Xiao, Li, Yu, Xiao, Hu, Tang, Zeng, He, Zeng, Ye, Xu: "MicroRNA-10b promotes migration and invasion through KLF4 and HOXD10 in human bladder cancer." in: Oncology reports, Vol. 31, Issue 4, pp. 1832-8, (2014) (PubMed).

    Zhou, Wu, Fu, Lv, Zhang: "Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer." in: Oncology letters, Vol. 7, Issue 5, pp. 1395-1400, (2014) (PubMed).

    Zhang, Sun, Zhang, Ge, Liu, Zhao, Lu, Fan: "Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5?2 signaling pathway." in: BMC cancer, Vol. 14, pp. 193, (2014) (PubMed).

    Jiang, Jin, Li, Zhang, Yang, Yang, Li, Yang, Ma: "Intermittent hypobaric hypoxia promotes atherosclerotic plaque instability in ApoE-deficient mice." in: High altitude medicine & biology, Vol. 14, Issue 2, pp. 175-80, (2013) (PubMed).

    Jin, Jiang, Yang, Zhang, Yang, Zhang, Li, Yang, Ma: "Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich diet." in: Biochemical and biophysical research communications, Vol. 428, Issue 1, pp. 86-92, (2012) (PubMed).

    Dong, Yu, Yang, Jiang, Zhang: "Expression of the reversion-inducing cysteine-rich protein with Kazal motifs and matrix metalloproteinase-14 in neuroblastoma and the role in tumour metastasis." in: International journal of experimental pathology, Vol. 91, Issue 4, pp. 368-73, (2010) (PubMed).

  • 抗原
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    别名
    MMP14 (MMP14 产品)
    别名
    MMP1 antibody, MMP-14 antibody, MMP-X1 antibody, MT-MMP antibody, MT-MMP 1 antibody, MT1-MMP antibody, MT1MMP antibody, MTMMP1 antibody, mmp-x1 antibody, mt1-mmp antibody, mtmmp1 antibody, AI325305 antibody, MT-MMP-1 antibody, sabe antibody, Mt1-mmp antibody, MT-MMPbeta antibody, cb386 antibody, sb:cb386 antibody, wu:fb72b09 antibody, mmp14 antibody, matrix metallopeptidase 14 antibody, matrix metallopeptidase 14 (membrane-inserted) antibody, matrix metallopeptidase 14b (membrane-inserted) antibody, matrix metallopeptidase 14a (membrane-inserted) antibody, matrix metallopeptidase 14 L homeolog antibody, MMP14 antibody, mmp14 antibody, Mmp14 antibody, mmp14b antibody, mmp14a antibody, mmp14.L antibody
    背景
    Matrix metalloproteinase-14, also called MT-MMP 1, is an enzyme that in humans is encoded by the MMP14 gene. The protein encoded by this gene is a member of the membrane-type MMP subfamily. This gene is mapped to 14q11.2. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7. It acts as a positive regulator of cell growth and migration via activation of MMP15.

    Synonyms: Matrix metallopeptidase 14 (membrane inserted) antibody|Matrix metalloproteinase 14 antibody|Matrix metalloproteinase-14 antibody|Membrane type 1 matrix metalloproteinase antibody|Membrane type 1 metalloprotease antibody|Membrane type matrix metalloproteinase 1 antibody|Membrane-type matrix metalloproteinase 1 antibody|Membrane-type-1 matrix metalloproteinase antibody|MMP 14 antibody|MMP X1 antibody|MMP-14 antibody|MMP-X1 antibody|Mmp14 antibody|MMP14_HUMAN antibody|MMPX1 antibody|MT MMP 1 antibody|MT-MMP 1 antibody|MT1 MMP antibody|MT1-MMP antibody|MT1MMP antibody|MTMMP 1 antibody|MTMMP1 antibody
    基因ID
    4323
    UniProt
    P50281
    途径
    Autophagy
客服