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SDHA 抗体 (AA 44-380)

SDHA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043324
发货至: 中国
  • 抗原 See all SDHA 抗体
    SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 44-380
    适用
    • 64
    • 46
    • 30
    • 9
    • 1
    人, 小鼠, 大鼠
    宿主
    • 64
    • 1
    克隆类型
    • 54
    • 11
    多克隆
    标记
    • 24
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SDHA antibody is un-conjugated
    应用范围
    • 39
    • 20
    • 15
    • 14
    • 13
    • 10
    • 8
    • 8
    • 6
    • 3
    • 2
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human SDHA recombinant protein (Position: S44-L380). Human SDHA shares 98.2% and 97.6% amino acid (aa) sequence identity with mouse and rat SDHA, respectively.
    亚型
    IgG
    Top Product
    Discover our top product SDHA Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))
    别名
    SDHA (SDHA 产品)
    别名
    CG17246 antibody, Dmel\\CG17246 antibody, Scs-fp antibody, Sdh antibody, Sdha antibody, scs-fp antibody, sdh antibody, CMD1GG antibody, FP antibody, PGL5 antibody, SDH1 antibody, SDH2 antibody, SDHF antibody, 1500032O14Rik antibody, 2310034D06Rik antibody, 4921513A11 antibody, C81073 antibody, im:7141001 antibody, zgc:56051 antibody, Fp antibody, sdha-b antibody, Succinate dehydrogenase, subunit A (flavoprotein) antibody, succinate dehydrogenase complex flavoprotein subunit A antibody, succinate dehydrogenase complex, subunit A, flavoprotein (Fp) antibody, succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog antibody, SdhA antibody, SDHA antibody, Sdha antibody, sdha antibody, sdha.S antibody
    背景
    Complex II of the mitochondrial respiratory chain, also known as succinate dehydrogenase or succinate:ubiquinone oxidoreductase, consists of 4 nuclear-encoded polypeptides, these are the flavoprotein subunit (SDHA), the iron sulfur protein subunit (SDHB), and the integral membrane protein subunits SDHC and SDHD. SDHA is an acronym for succinate dehydrogenase complex subunit A. The succinate dehydrogenase (SDH) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone => fumarate + ubiquinol). The SDHA subunit is connected to the SDHB subunit on the hydrophilic, catalytic end of the complex, and weighs 72.7 kDA. Mutations in the SDHA subunit have a distinct pathology from mutations in the SDHB/SDHC/SDHD subunits, it is the only subunit to never have shown tumor suppressor behaviour. Heterozygous carriers of an SDHA mutation do not develop paragangliomas as has been seen for mutations in the other subunits. This appears to be due to the expression of two similar SDHA genes (Types I and II) in the paraganglia system.

    Synonyms: MD1GG antibody|DHSA_HUMAN antibody|Flavoprotein subunit of complex II antibody|FP antibody| PGL5 antibody|SDH 2 antibody|SDH1 antibody|SDH2 antibody|SDHA antibody|SDHF antibody| Succinate dehydrogenase [ubiquinone] flavoprotein subunit antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit mitochondrial antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial antibody|Succinate dehydrogenase complex flavoprotein subunit antibody|Succinate dehydrogenase complex flavoprotein subunit precursor antibody|Succinate dehydrogenase complex subunit A antibody| Succinate dehydrogenase complex subunit A flavoprotein antibody
    基因ID
    6389
    UniProt
    P31040
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