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ADAMTS4 抗体 (C-Term)

ADAMTS4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043192
发货至: 中国
  • 抗原 See all ADAMTS4 抗体
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    抗原表位
    • 15
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 820-837, C-Term
    适用
    • 80
    • 47
    • 19
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 72
    • 10
    • 4
    克隆类型
    • 77
    • 9
    多克隆
    标记
    • 40
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAMTS4 antibody is un-conjugated
    应用范围
    • 63
    • 29
    • 15
    • 13
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Tested with WB in Human,Mouse,Rat.
    序列
    RRAQILEILR RRPWAGRK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
    Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAM-TS 4/ADAM-TS4/ADAMTS-4)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4(820-837aa RRAQILEILRRRPWAGRK), different from the related rat and mouse sequences by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ADAMTS4 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Liu, Tian, Zhou, Wang, Gou, Zhang, Wang, Shen, Zhang, Zhang: "Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat." in: BMC musculoskeletal disorders, Vol. 16, pp. 342, (2016) (PubMed).

    Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

  • 抗原
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    别名
    ADAMTS4 (ADAMTS4 产品)
    别名
    3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
    背景
    ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

    Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 4 antibody|A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 4 antibody|A disintegrin like and metalloprotease with thrombospondin type 1 motif 4 antibody|ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody|ADAM TS 4 antibody|ADAM TS4 antibody|ADAM-TS 4 antibody|ADAM-TS4 antibody|ADAMTS 2 antibody|ADAMTS 4 antibody|ADAMTS-4 antibody|ADAMTS2 antibody|ADAMTS4 antibody|ADAMTS4 protein antibody|ADMP 1 antibody|ADMP-1 antibody|ADMP1 antibody|Aggrecanase 1 antibody|Aggrecanase-1 antibody|Aggrecanase1 antibody|ATS4_HUMAN antibody|KIAA0688 antibody
    UniProt
    O75173
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