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PAD4 抗体 (Middle Region)

Name: PAD4 抗体 (Middle Region)
SKU: ABIN3042934
Availability: OutOfStock

PADI4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Anti-PADI4/PAD4 antibody, Western blotting Lane 1: PANC Cell Lysate Lane 2: 293T Cell Lysate

1 image

产品编号 ABIN3042934

发货至: 中国

Datasheet as PDF

抗原 See all PAD4 (PADI4) 抗体

PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
抗原表位
15

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 492-512, Middle Region
适用
54

9

8

2

1

1

1

1

1

1

1

1

1

1
人
宿主
40

12

1
兔
Compatible Secondaries
克隆类型
44

10
多克隆
标记
40

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PAD4 antibody is un-conjugated
应用范围
34

20

16

14

13

13

9

6

4

3

3

2

2

2

1

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Protein-arginine deiminase type-4(PADI4) detection. Tested with WB in Human.

序列

ASPRSCYKLF QEQQNEGHGE A

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Protein-arginine deiminase type-4(PADI4) detection. Tested with WB in Human.
Gene Name: peptidyl arginine deiminase, type IV
Protein Name: Protein-arginine deiminase type-4

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PADI4(492-512aa ASPRSCYKLFQEQQNEGHGEA).

亚型

IgG

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anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (Center) antibody
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anti-Peptidyl Arginine Deiminase, Type IV (PADI4) antibody
PADI4 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (N-Term) antibody
Verified PADI4 适用: 人 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 374-550) antibody
PADI4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 299-588) antibody
PADI4 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5E7 unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 1-300) antibody
PADI4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) antibody
PADI4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (N-Term) antibody
PADI4 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 299-588) antibody
PADI4 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PADI4 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
抗原

PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

别名

PADI4 (PADI4 产品)

别名

PAD antibody, PAD4 antibody, PADI5 antibody, PDI4 antibody, PDI5 antibody, Pad4 antibody, Pdi4 antibody, peptidyl arginine deiminase 4 antibody, peptidyl arginine deiminase, type IV antibody, PADI4 antibody, Padi4 antibody

背景

PADI4(Peptidylarginine Deiminase, Type IV), also known as PAD or PAD4, is a human protein which in humans is encoded by the PADI4 gene. Peptidylarginine deiminases, such as PADI4, make up a family of posttranslational modification enzymes that convert arginine residues to citrulline residues in the presence of calcium ion(Nakashima et al., 1999). Suzuki et al.(2003) found from sequence data that the PADI4 gene maps to 1p36. Cuthbert et al.(2004) described a process, deimination, that converts histone arginine to citrulline and antagonizes arginine methylation. They showed that PADI4 specifically deiminated arg2, arg8, arg17, and arg26 in the H3 tail. Deimination by PADI4 prevented arginine methylation by CARM1. Dimethylation of arginines prevented deimination by PADI4, although monomethylation still allowed deimination to take place. In vivo targeting experiments on an endogenous promoter demonstrated that PADI4 could repress hormone receptor-mediated gene induction. PADI4 was recruited to the pS2 promoter following hormone induction when the gene was transcriptionally downregulated, consistent with a repressive role for PADI4.

Synonyms: EC 3.5.3.15 antibody|HL 60 PAD antibody|HL-60 PAD antibody|PAD 4 antibody|PAD antibody|PADI 4 antibody|PADI 5 antibody|PADI H protein antibody|Padi4 antibody|PADI4_HUMAN antibody|PADI5 antibody|PDI 4 antibody|PDI 5 antibody|PDI4 antibody|PDI5 antibody|Peptidyl arginine deiminase type IV antibody|Peptidyl arginine deiminase type V antibody|Peptidylarginine deiminase IV antibody|Protein arginine deiminase antibody|Protein arginine deiminase type 4 antibody|Protein arginine deiminase type IV antibody|Protein-arginine deiminase type IV antibody|Protein-arginine deiminase type-4 antibody