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- 抗原 See all PCSK9 抗体
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
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抗原表位
- AA 671-687, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCSK9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 9(PCSK9) detection. Tested with WB, IHC-P in Human.
- 序列
- AVTAVAICCR SRHLAQA
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 9(PCSK9) detection. Tested with WB, IHC-P in Human.
Gene Name: proprotein convertase subtilisin/kexin type 9
Protein Name: Proprotein convertase subtilisin/kexin type 9 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PCSK9(671-687aa AVTAVAICCRSRHLAQA).
- 亚型
- IgG
- Top Product
- Discover our top product PCSK9 Primary Antibody
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anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (C-Term) antibody
PCSK9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 164-428) antibodyPCSK9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (C-Term) antibodyVerified PCSK9 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 153-183), (N-Term) antibodyPCSK9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19130 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 144-173) antibodyPCSK9 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 479-508) antibodyPCSK9 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) antibodyPCSK9 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 479-508), (C-Term) antibodyPCSK9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18880 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 153-380) antibodyPCSK9 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 164-428) antibodyPCSK9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
- 别名
- PCSK9 (PCSK9 产品)
- 别名
- FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, AI415265 antibody, AI747682 antibody, Narc1 antibody, proprotein convertase subtilisin/kexin type 9 antibody, proprotein convertase subtilisin/kexin type 9 L homeolog antibody, PCSK9 antibody, pcsk9.L antibody, pcsk9 antibody, Pcsk9 antibody
- 背景
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Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, PCSK9 was mapped to chromosome 1p32. This gene is a crucial player in the regulation of plasma cholesterol homeostasis. It may prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation. PCSK9 can induce ubiquitination of LDLR leading to its subsequent degradation. This gene is involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway.
Synonyms: Convertase subtilisin/kexin type 9 preproprotein antibody|FH3 antibody|HCHOLA3 antibody|Hypercholesterolemia autosomal dominant 3 antibody|LDLCQ1 antibody|NARC 1 antibody|NARC-1 antibody|NARC1 antibody|Neural apoptosis regulated convertase 1 antibody|Neural apoptosis-regulated convertase 1 antibody|PC 9 antibody|PC9 antibody|PCSK 9 antibody|PCSK9 antibody|PCSK9_HUMAN antibody|Proprotein convertase 9 antibody|Proprotein convertase PC9 antibody|Proprotein convertase subtilisin/kexin type 9 antibody|PSEC0052 antibody|Subtilisin/kexin like protease PC9 antibody|Subtilisin/kexin-like protease PC9 antibody
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