Survivin 抗体 (AA 1-142)
(8 references)-
- 抗原 See all Survivin (BIRC5) 抗体
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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抗原表位
- AA 1-142
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Survivin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB, IHC-P, ELISA in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: baculoviral IAP repeat containing 5
Protein Name: Baculoviral IAP repeat-containing protein 5 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human Survivin recombinant protein(Position: M1-D142).
- 亚型
- IgG
- Top Product
- Discover our top product BIRC5 Primary Antibody
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anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 85-142) antibody
BIRC5 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-100) antibodyBIRC5 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 5B10 unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 1# unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (pThr117) antibodyBIRC5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) antibodyBIRC5 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1H5 unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (C-Term) antibodyBIRC5 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Species: Human, The detection limit for BIRC5 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Human
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14034-9, (2016) (PubMed).
: "Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer drug repurposing." in: Oncology letters, Vol. 11, Issue 5, pp. 3265-3272, (2016) (PubMed).
: "Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation." in: PLoS ONE, Vol. 9, Issue 4, pp. e95912, (2014) (PubMed).
: "The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells." in: Tumour biology, Vol. 35, Issue 6, pp. 5401-7, (2014) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1." in: Biochemical and biophysical research communications, Vol. 434, Issue 4, pp. 809-14, (2013) (PubMed).
: "Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy." in: International journal of ophthalmology, Vol. 5, Issue 3, pp. 293-6, (2012) (PubMed).
: "Radiosensitivity of human colon cancer cell enhanced by immunoliposomal docetaxel." in: World journal of gastroenterology, Vol. 11, Issue 26, pp. 4003-7, (2005) (PubMed).
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: "Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14034-9, (2016) (PubMed).
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- 抗原
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 别名
- BIRC5 (BIRC5 产品)
- 别名
- AP14 antibody, API4 antibody, EPR-1 antibody, AAC-11 antibody, Api4 antibody, TIAP antibody, survivin40 antibody, bir5a antibody, survivin antibody, BIR1 antibody, Su2 antibody, XBIR1 antibody, XSurvivin1 antibody, Xsvv1 antibody, api4 antibody, bir1-A antibody, epr-1 antibody, svv1 antibody, xSurvivin antibody, xsurv antibody, Su1 antibody, birc5.2 antibody, svv2 antibody, xSurvivin2 antibody, bir5b antibody, SIX antibody, birc5.2-a antibody, birc5.2-b antibody, baculoviral IAP repeat containing 5 antibody, baculoviral IAP repeat-containing 5 antibody, baculoviral IAP repeat containing 5a antibody, baculoviral IAP repeat-containing 5, gene 1 L homeolog antibody, baculoviral IAP repeat containing 5 L homeolog antibody, baculoviral IAP repeat containing 5b antibody, baculoviral IAP repeat containing 5 S homeolog antibody, BIRC5 antibody, Birc5 antibody, birc5a antibody, birc5.1.L antibody, birc5.2.L antibody, birc5b antibody, birc5.2.S antibody
- 背景
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Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis(IAP) family. The survivin gene contains 4 exons. The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.
Synonyms: API4 antibody|Apoptosis Inhibitor 4 antibody|Apoptosis inhibitor survivin antibody|Apoptosis inhibitor4 antibody|Baculoviral IAP repeat containing 5 antibody|Baculoviral IAP repeat containing protein 5 antibody|Baculoviral IAP repeat-containing protein 5 antibody|BIRC 5 antibody|BIRC5 antibody|EPR 1 antibody|IAP4 antibody|Survivin variant 3 alpha antibody|SVV antibody|TIAP antibody - UniProt
- O15392
- 途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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