电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Desmoglein 3 抗体 (C-Term)

DSG3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042664
发货至: 中国
  • 抗原 See all Desmoglein 3 (DSG3) 抗体
    Desmoglein 3 (DSG3)
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 981-999, C-Term
    适用
    • 66
    • 21
    • 16
    宿主
    • 60
    • 26
    克隆类型
    • 60
    • 26
    多克隆
    标记
    • 35
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoglein 3 antibody is un-conjugated
    应用范围
    • 63
    • 35
    • 19
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Desmoglein-3(DSG3) detection. Tested with WB in Human.
    序列
    QLRGSHTMLC TEDPCSRLI
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Desmoglein-3(DSG3) detection. Tested with WB in Human.
    Gene Name: desmoglein 3
    Protein Name: Desmoglein-3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 3(981-999aa QLRGSHTMLCTEDPCSRLI ).
    亚型
    IgG
    Top Product
    Discover our top product DSG3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Desmoglein 3 (DSG3)
    别名
    DSG3 (DSG3 产品)
    别名
    DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
    背景
    Desmoglein3 is also known as PVA(Pemphigus Vulgaris Antigen). Pemphigus vulgaris(PV) and pemphigus foliaceus(PF) are autoimmune diseases of the skin which have as target antigens 2 different members of the desmoglein subfamily of the desmosomal cadherins: pemphigus vulgaris antigen(PVA, or desmoglein-3) in the case of PV and desmoglein I in the case of PF. The DSG3 gene, like the genes for DSG1 and DSG2, is located on chromosome 18. The human DSG3 gene consists of 15 exons and spans more than 23 kb. DSG3 and DSG1 are the autoantigens of pemphigus vulgaris and pemphigus foliaceus, respectively. DSG3 and DSG1 are the target antigens in PNP, and IgG autoantibodies against DSG3 in PNP sera play a pathogenic role in the loss of keratinocyte adhesion and blistering.

    Synonyms: 130 kD pemphigus vulgaris antigen antibody|130 kDa pemphigus vulgaris antigen antibody|Bal antibody|Balding antibody|Cadherin family member 6 antibody|CDHF 6 antibody|CDHF6 antibody|Desmoglein 3 antibody|Desmoglein 3 precursor antibody|Desmoglein3 antibody|DKFZp686P23184 antibody|DSG 3 antibody|DSG3 antibody|Pemphigus vulgaris antigen antibody|PVA antibody
    UniProt
    P32926
You are here:
客服