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- 抗原 See all PINX1 抗体
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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抗原表位
- AA 54-83, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PINX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for PIN2/TERF1-interacting telomerase inhibitor 1(PINX1) detection. Tested with WB in Human.
- 序列
- DHIKVQVKNN HLGLGATINN EDNWIAHQDD
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for PIN2/TERF1-interacting telomerase inhibitor 1(PINX1) detection. Tested with WB in Human.
Gene Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PINX1 (54-83aa DHIKVQVKNNHLGLGATINNEDNWIAHQDD), different from the related mouse and rat sequences by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PINX1 Primary Antibody
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anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-100) antibody
PINX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Internal Region) antibodyPINX1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 85-133) antibodyPINX1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 151-299) antibodyPINX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 225-237) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (N-Term) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 35-84) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 兔, 豚鼠, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 107-156) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 兔, 猴, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-221) antibodyPINX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 127-328) antibodyPINX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- 别名
- PINX1 (PINX1 产品)
- 别名
- PINX1 antibody, LPTL antibody, LPTS antibody, 2210403I16Rik antibody, 2610028A01Rik antibody, 67-11-3 antibody, AU024023 antibody, LPTS1 antibody, RGD1566025 antibody, PIN2/TERF1 interacting telomerase inhibitor 1 antibody, PIN2/TERF1 interacting, telomerase inhibitor 1 antibody, PINX1 antibody, Pinx1 antibody
- 背景
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PINX1, also known as PIN2 interacting protein 1, is a telomerase inhibitor and a possible tumor suppressor. It is mapped to 8p23. Over-expression of PINX1 results in decreased telomerase activity, telomere shortening, and induction of crisis. Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres. PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity. The PINX1 budding yeast orthologue Gnop1 inhibits telomerase by isolating the uncomplexed TERT protein so that it cannot associate with the telomerase template RNA, which prevents telomerase from being assembled. However, in humans, PINX1 impedes already assembled telomerase.
Synonyms: 67-11-3 protein antibodyFLJ20565 antibody|Hepatocellular carcinoma-related putative tumor suppressor antibody|Liver-related putative tumor suppressor antibody|LPTL antibody|LPTS antibody|MGC8850 antibody|OTTHUMP00000224984 antibody|OTTHUMP00000224985 antibody| OTTHUMP00000224986 antibody|OTTHUMP00000225053 antibody|OTTHUMP00000225054 antibody|PIN2 interacting protein 1 antibody|Pin2-interacting protein X1 antibody|PIN2/TERF1-interacting telomerase inhibitor 1 antibody|PINX1 antibody|PINX1_HUMAN antibody|Protein 67-11-3 antibody|TRF1-interacting protein 1 antibody - 基因ID
- 54984
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