(1 reference)-
- 抗原 See all Fascin (FSCN1) 抗体
- Fascin (FSCN1)
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抗原表位
- AA 42-73, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fascin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Fascin(FSCN1) detection. Tested with WB in Human,Rat.
- 序列
- KKQIWTLEQP PDEAGSAAVC LRSHLGRYLA AD
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Fascin(FSCN1) detection. Tested with WB in Human,Rat.
Gene Name: fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
Protein Name: Fascin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Fascin (42-73aa KKQIWTLEQPPDEAGSAAVCLRSHLGRYLAAD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product FSCN1 Primary Antibody
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anti-Fascin (FSCN1) antibody
FSCN1 适用: 人 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal FSCN1-417 unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人, 大鼠 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal FSCN1-418 unconjugated
anti-Fascin (FSCN1) (AA 11-110) antibodyFSCN1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal FSCN1-416 unconjugated
anti-Fascin (FSCN1) (AA 394-493) antibodyFSCN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (pSer39) antibodyFSCN1 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 322-350) antibodyFSCN1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 2-187) antibodyFSCN1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 93-142) antibodyFSCN1 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 斑马鱼, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人, 大鼠 IHC, IHC (p) 宿主: 小鼠 Monoclonal FCN01 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." in: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).
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: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." in: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).
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- 抗原
- Fascin (FSCN1)
- 别名
- FSCN1 (FSCN1 产品)
- 别名
- CG15331 antibody, CG1536 antibody, CG32858 antibody, Dmel\\CG32858 antibody, SN antibody, Sn antibody, fs(1)A1057 antibody, fs(1)K1421 antibody, fs(1)K418 antibody, fs(1)K473 antibody, fs(1)K743 antibody, fs(1)M45 antibody, p55 antibody, snl antibody, MGC75811 antibody, fscn1 antibody, sb:cb589 antibody, zgc:153632 antibody, AI663989 antibody, Fan1 antibody, fascin-1 antibody, Fascin antibody, fscn antibody, FAN1 antibody, HSN antibody, SNL antibody, fascin antibody, singed antibody, fascin actin-bundling protein 1 antibody, fascin actin-bundling protein 1a antibody, fascin actin-bundling protein 1 L homeolog antibody, sn antibody, fscn1 antibody, fscn1a antibody, Fscn1 antibody, fscn1.L antibody, FSCN1 antibody
- 背景
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Fascin is an actin cross-linking protein. The Fascin gene contains 5 exons and spans 7 kb. It is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin (from the Latin for bundle) is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins. It is calcium insensitive and monomeric. Fascin binds beta-catenin, and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. The role of Fascin in regulating cytoskeletal structures for the maintenance of cell adhesion, coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective. Abnormal fascin expression or function has been implicated in breast cancer, colon cancer, esophageal squamous cell carcinoma, gallbladder cancer and prostate cancer.
Synonyms: 55 kDa actin bundling protein antibody|55 kDa actin-bundling protein antibody|Actin bundling protein antibody|actin bundling protein, 55-KD antibody|FAN 1 antibody|FAN1 antibody|Fascin 1 antibody|Fascin antibody|Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus) antibody|Fascin homolog 1 antibody|Fascin, sea urchin, homolog of, 1 antibody|Fascin1 antibody| FLJ38511 antibody|FSCN 1 antibody|FSCN1 antibody|FSCN1_HUMAN antibody|HSN antibody|p55 antibody|Singed (Drosophila) like (sea urchin fascin homolog like) antibody|Singed drosophila homolog like antibody|Singed like (fascin homolog sea urchin) (Drosophila) antibody| Singed like (fascin homolog sea urchin) antibody|Singed like protein antibody|Singed, drosophila, homolog of antibody|Singed-like protein antibody|SNL antibody|Strongylocentrotus purpuratus antibody - 基因ID
- 6624
- UniProt
- Q16658
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