NOTCH2 抗体 (cleaved, Intracellular, N-Term)
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Quick Overview for NOTCH2 抗体 (cleaved, Intracellular, N-Term) (ABIN303375)
抗原
See all NOTCH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- cleaved, Intracellular, N-Term
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特异性
- This antibody recognises Notch Homolog 2 (NOTCH2).
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纯化方法
- Sterile filtration.
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免疫原
- Synthetic Peptide corresponding to Amino acid residues of human Notch 2 located near the N-terminal sequence of the Cleaved N Intracellular Domain (NICD).
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anti-Notch 2 (NOTCH2) antibody
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Asp1733), (cleaved) antibodyNOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (C-Term) antibodyNOTCH2 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 1501-1700) antibodyNOTCH2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2251-2466) antibodyNOTCH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 59-250) antibodyNOTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (cleaved), (Internal Region) antibodyNOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2242-2471) antibodyNOTCH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2421-2471) antibodyNOTCH2 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2250-2300) antibodyNOTCH2 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections (1/500). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid cycles of freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store vial at-20 °C prior to opening. Aliquot contents and freeze at-20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature.
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- NOTCH2 (Notch 2 (NOTCH2))
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别名
- NOTCH2
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背景
- Notch is synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase (S1 cleavage) in the trans-golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC). Following ligand binding, it is cleaved (S2 cleavage) by TNF-alpha converting enzyme (TACE) to yield a membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). This fragment is then cleaved by presenilin-dependent gamma-secretase (S3 cleavage) to release the intracellular domain (NICD) from the membrane.Synonyms: Neurogenic locus notch homolog protein 2, Notch 2, hN2
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基因ID
- 4853
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NCBI登录号
- NP_001186930
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UniProt
- Q04721
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
-
