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- 抗原 See all PCSK9 抗体
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
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抗原表位
- AA 671-687
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCSK9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids 671-687 (AVTAVAICCRSRHLAQA-human) were used as the immunogen for this PCSK9 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PCSK9 Primary Antibody
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anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (C-Term) antibody
PCSK9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 164-428) antibodyPCSK9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (C-Term) antibodyVerified PCSK9 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 153-183), (N-Term) antibodyPCSK9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19130 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 479-508) antibodyPCSK9 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 144-173) antibodyPCSK9 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) antibodyPCSK9 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 479-508), (C-Term) antibodyPCSK9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18880 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 153-380) antibodyPCSK9 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 164-428) antibodyPCSK9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting points. Titration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PCSK9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
- 别名
- PCSK9 (PCSK9 产品)
- 背景
- Proprotein convertase subtilisin/kexin type 9 is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, PCSK9 was mapped to chromosome 1p32. This gene is a crucial player in the regulation of plasma cholesterol homeostasis. It may prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation. It can induce ubiquitination of LDLR leading to its subsequent degradation. This gene is involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway.
- UniProt
- Q8NBP7
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