电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NOXA1 抗体 (Middle Region)

NOXA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031937
发货至: 中国
  • 抗原 See all NOXA1 抗体
    NOXA1 (NADPH Oxidase Activator 1 (NOXA1))
    抗原表位
    • 15
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 27
    • 16
    • 15
    宿主
    • 55
    • 2
    克隆类型
    • 57
    多克隆
    标记
    • 15
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NOXA1 antibody is un-conjugated
    应用范围
    • 53
    • 26
    • 26
    • 23
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human NADPH oxidase activator 1 (RQVPRGEVFRPHRWHLKHLE) was used as the immunogen for this NOXA1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product NOXA1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the NOXA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the NOXA1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    NOXA1 (NADPH Oxidase Activator 1 (NOXA1))
    别名
    NOXA1 (NOXA1 产品)
    别名
    NY-CO-31 antibody, SDCCAG31 antibody, p51NOX antibody, NADPH oxidase activator 1 antibody, NOXA1 antibody, Noxa1 antibody
    背景
    NADPH oxidase activator 1, also called NOX Activator 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene. Hartz(2007) mapped the gene to chromosome 9q34.3 based on an alignment of the protein sequence with the genomic sequence(build 36.1). Banfi et al.(2003) mapped the mouse gene to chromosome 2. Using yeast 2-hybrid assays, Takeya et al.(2003) showed that the human protein interacted with constitutively active forms of RAC1 and RAC2. In vitro binding assays revealed that NOXA1 bound GTP-bound RAC1, but not GDP-bound RAC1. It also bound p47-PHOX (NCF1) and p41-NOX (NOXO1), and trp436 within the SH3 domain of NOXA1 was required for these interactions. Human cell lines or COS-7 cells cotransfected with NOXA1/p51-NOX and p41-NOX and either gp91-PHOX(CYBB) or NOX1 produced superoxide. Cells individually transfected with NOX1, p41-NOX, or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production.
    UniProt
    Q86UR1
You are here:
客服