电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL4 Receptor 抗体 (Middle Region)

IL4R 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031482
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 抗体
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    抗原表位
    • 16
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 53
    • 37
    • 22
    宿主
    • 67
    • 9
    • 2
    • 2
    • 1
    克隆类型
    • 72
    • 8
    • 1
    多克隆
    标记
    • 44
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IL4 Receptor antibody is un-conjugated
    应用范围
    • 74
    • 25
    • 23
    • 15
    • 14
    • 13
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human IL4R (TKWHNSYREPFEQH) was used as the immunogen for this IL4R antibody.
    亚型
    IgG
    Top Product
    Discover our top product IL4R Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the IL4R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the IL4R antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL4R (IL4R 产品)
    别名
    IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
    背景
    IL4R (Interleukin 4 receptor) is a human gene that encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. The gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines. IL4 plays a major role in immunoglobulin E(IgE) production. Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor. IL4 interacts with IL4R with high affinity, leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines, to create a type I receptor, or with IL13RA1 to form a type II receptor. The IL4R gene contains 12 exons and the protein is a complex of at least two components, one of which is a novel affinity converting subunit that is critical for cellular signal transduction.
    UniProt
    P24394
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
You are here:
客服