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IRF4 抗体 (AA 272-451)

IRF4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031419
发货至: 中国
  • 抗原 See all IRF4 抗体
    IRF4 (Interferon Regulatory Factor 4 (IRF4))
    抗原表位
    • 9
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 272-451
    适用
    • 44
    • 19
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 35
    • 6
    • 2
    • 1
    • 1
    克隆类型
    • 36
    • 9
    多克隆
    标记
    • 38
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF4 antibody is un-conjugated
    应用范围
    • 37
    • 15
    • 10
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 272-451) was used as the immunogen for this IRF4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product IRF4 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the IRF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the IRF4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    IRF4 (Interferon Regulatory Factor 4 (IRF4))
    别名
    IRF4 (MUM1) (IRF4 产品)
    别名
    LSIRF antibody, MUM1 antibody, NF-EM5 antibody, AI385587 antibody, IRF-4 antibody, Spip antibody, IRF4 antibody, si:ch73-170d1.2 antibody, irf4 antibody, interferon regulatory factor 4 antibody, interferon regulatory factor 4a antibody, Interferon regulatory factor 4 antibody, PWWP domain-containing protein MUM1 antibody, IRF4 antibody, Irf4 antibody, irf4a antibody, irf4 antibody, LOC612320 antibody, LOC100068881 antibody
    背景
    Interferon regulatory factor 4, also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. Additionally, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.
    基因ID
    3662
    途径
    Chromatin Binding
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