PPP1R13L 抗体 (Isoform 1)
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- 抗原 See all PPP1R13L 抗体
- PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))
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抗原表位
- Isoform 1
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适用
- 人, 小鼠, 犬, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP1R13L antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- ,Species:Human, Bovine, Dog and Mouse.
- 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide corresponding to Amino Acids 780-797 of human iASPP (isoform 1) protein.
- Top Product
- Discover our top product PPP1R13L Primary Antibody
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anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) antibody
PPP1R13L 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 1-828) antibodyPPP1R13L 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 75-125) antibodyPPP1R13L 适用: 人 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 780-797), (Isoform 1) antibodyPPP1R13L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (Middle Region) antibodyPPP1R13L 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 83-102) antibodyPPP1R13L 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 134-166) antibodyPPP1R13L 适用: 人 WB, IF 宿主: 兔 Polyclonal RB53806 unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 15-100) antibodyPPP1R13L 适用: 人, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 455-485) antibodyPPP1R13L 适用: 人 WB 宿主: 兔 Polyclonal RB53804 unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) (AA 253-351) antibodyPPP1R13L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunofluorescence. Western Blot (1/1000-1/5000). ELISA (1/40000-1/160000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.19 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C. Dilute only prior to immediate use.
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- 抗原
- PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))
- 别名
- PPP1R13L (PPP1R13L 产品)
- 别名
- AV260376 antibody, IASPP antibody, Nkip1 antibody, wa3 antibody, zgc:113058 antibody, NKIP1 antibody, RAI antibody, RAI4 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 13 like antibody, protein phosphatase 1, regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like L homeolog antibody, Ppp1r13l antibody, ppp1r13l antibody, PPP1R13L antibody, ppp1r13l.L antibody
- 背景
- ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. This protein also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. iASPP is predominantly a cytoplasmic protein (isoform 1) but can also be found in the nucleus (isoform 2). iASPP is highly expressed in heart, placenta and prostate and is weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. The N-terminal region of isoform 1 is required for cytoplasmic localization. Defects in iASPP may be a cause of certain breast cancers and the protein is overexpressed in many patients suffering from breast carcinomas and expressing a wild-type p53/TP53 protein.Synonyms: IASPP, Inhibitor of ASPP protein, NFkB-interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13BL, RAI, RelA-associated inhibitor
- 基因ID
- 10848
- NCBI登录号
- NP_001135974
- UniProt
- Q8WUF5
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