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HRH3 抗体 (C-Term)

HRH3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031207
发货至: 中国
  • 抗原 See all HRH3 抗体
    HRH3 (Histamine Receptor H3 (HRH3))
    抗原表位
    • 15
    • 15
    • 15
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 84
    • 49
    • 32
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 84
    • 3
    • 1
    克隆类型
    • 86
    • 2
    多克隆
    标记
    • 42
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HRH3 antibody is un-conjugated
    应用范围
    • 74
    • 26
    • 21
    • 18
    • 18
    • 13
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human HRH3 (CPQKLKIQPHSSLEHCWK) was used as the immunogen for this HRH3 antibody.
    亚型
    IgG
    Top Product
    Discover our top product HRH3 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the HRH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the HRH3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    HRH3 (Histamine Receptor H3 (HRH3))
    别名
    HRH3 (HRH3 产品)
    背景
    The histamine receptor H3(HRH3) is a presynaptic autoreceptor on histamine neurons in the brain and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. The deduced 445-amino acid HRH3 protein contains 7 predicted transmembrane domains. And it shares 22 % and 21.4 % amino acid sequence homology with the H1(HRH1) and H2(HRH2) receptors, respectively. The expression of recombinant HRH3 in a variety of cell lines conferred an ability to inhibit adenylate cyclase in response to histamine, but not to acetylcholine or any other biogenic amine. Additionally, HRH3 was most notably observed throughout the thalamus, the ventromedial hypothalamus, and the caudate nucleus. Strong expression was also seen in layers II, V, and VIb of the cerebral cortex, in the pyramidal layers of the hippocampus, and in olfactory tubercle.
    UniProt
    Q9Y5N1
    途径
    cAMP Metabolic Process, Feeding Behaviour
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