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Aromatase 抗体 (C-Term)

CYP19A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030680
发货至: 中国
  • 抗原 See all Aromatase (CYP19A1) 抗体
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    抗原表位
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    C-Term
    适用
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    宿主
    • 69
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    克隆类型
    • 73
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    多克隆
    标记
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    This Aromatase antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human Aromatase (KNMLEMIFTPRNSDRCLEH) was used as the immunogen for this Aromatase antibody.
    亚型
    IgG
    Top Product
    Discover our top product CYP19A1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Aromatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Aromatase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    别名
    Aromatase (CYP19A1 产品)
    别名
    ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, CYPXIX antibody, P-450AROM antibody, Aromatase antibody, Cyp19 antibody, Cyp19a antibody, p450arom antibody, P450 arom antibody, aro antibody, cyp19 antibody, cyp19a antibody, p450arom-A antibody, P450AROM antibody, Ar antibody, ArKO antibody, Int-5 antibody, Int5 antibody, CYP19P1 antibody, CYP19A1 antibody, CYP19a1 antibody, P450aromA antibody, ar1 antibody, cypXIX antibody, etID309862.18 antibody, zgc:136541 antibody, AroB antibody, CYP19a2 antibody, P450aromB antibody, cyp19b antibody, zgc:92614 antibody, cyp19a1 antibody, cytochrome P450 family 19 subfamily A member 1 antibody, cytochrome P450, family 19, subfamily a, polypeptide 1 antibody, cytochrome P450 family 19 subfamily A member 1 L homeolog antibody, aromatase antibody, cytochrome P450 aromatase antibody, cytochrome P450, family 19, subfamily A, polypeptide 1 antibody, cytochrome P450 19A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, cytochrome P450, family 19 antibody, cytochrome P450, family 19, subfamily A, polypeptide 1a antibody, cytochrome P450, family 19, subfamily A, polypeptide 1b antibody, cytochrome P450 19A1-like antibody, CYP19A1 antibody, Cyp19a1 antibody, cyp19a1.L antibody, SAV_2383 antibody, pfcyp19b-tstr antibody, CYP19 antibody, cyp19a1a antibody, cyp19a1b antibody, LOC101174651 antibody
    背景
    Aromatase is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The CYP19 gene spans at least 70 kb of genomic DNA and contains 10 exons. By in situ hybridization, the ARO gene is mapped to 15q21.1. The aromatase enzyme can be found in many tissues including gonads, brain, adipose tissue, placenta, blood vessels, skin, bone, and endometrium, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens, which can cause gynecomastia.
    UniProt
    P11511
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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