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CARM1 抗体 (Middle Region)

CARM1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030541
发货至: 中国
  • 抗原 See all CARM1 抗体
    CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
    抗原表位
    • 18
    • 15
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    • 8
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    • 2
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    Middle Region
    适用
    • 93
    • 34
    • 32
    • 5
    • 4
    • 4
    • 2
    • 2
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    • 1
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    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 84
    • 8
    • 2
    克隆类型
    • 86
    • 8
    多克隆
    标记
    • 42
    • 8
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    This CARM1 antibody is un-conjugated
    应用范围
    • 74
    • 47
    • 26
    • 26
    • 22
    • 14
    • 12
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human CARM1/PRMT4 (HLAPFTDEQLYMEQFTKA) was used as the immunogen for this PRMT4 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product CARM1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the PRMT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PRMT4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
    别名
    PRMT4 (CARM1 产品)
    别名
    NV18905 antibody, prmt4 antibody, PRMT4 antibody, Prmt4 antibody, si:dkey-204f11.63 antibody, zgc:100805 antibody, coactivator associated arginine methyltransferase 1 antibody, coactivator associated arginine methyltransferase 1 L homeolog antibody, coactivator-associated arginine methyltransferase 1 antibody, histone-arginine methyltransferase CARM1 antibody, CARM1 antibody, carm1.L antibody, Carm1 antibody, carm1 antibody, LOC100352221 antibody
    背景
    CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. This gene is mapped to 19p13.2. CARM1/PRMT4 is a regulator of cyclin E1 and DHFR mRNA expression. Its main function includes catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. PRMT4 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.
    UniProt
    Q86X55
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
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