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IL2RG 抗体 (Middle Region)

IL2RG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029733
发货至: 中国
  • 抗原 See all IL2RG 抗体
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    抗原表位
    • 16
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 71
    • 26
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    • 3
    • 1
    宿主
    • 60
    • 10
    • 9
    克隆类型
    • 63
    • 16
    多克隆
    标记
    • 34
    • 9
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This IL2RG antibody is un-conjugated
    应用范围
    • 54
    • 31
    • 28
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human IL-2 Receptor gamma subunit (HYWYKNSDNDKVQKC) was used as the immunogen for this IL-2 Receptor antibody.
    亚型
    IgG
    Top Product
    Discover our top product IL2RG Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the IL-2 Receptor gamma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    别名
    IL-2 Receptor (Gamma Subunit) (IL2RG 产品)
    别名
    Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody
    背景
    Interleukin 2 receptor gamma, also known as Common gamma chain or CD132, is a cytokine recepter subunit that is common to the receptr complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 recepter. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte(white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, the IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL-2 receptor. Lymphocytes expressing the common gama chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gama subunit by several receptors explains why humans and mice that lack IL-2 entirely show milder symptoms than those with IL2RG deficiency.
    UniProt
    P31785
    途径
    JAK/STAT Signaling, Growth Factor Binding
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