TRPC6 抗体 (Middle Region)
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- 抗原 See all TRPC6 抗体
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPC6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of human TRPC6 (HDYFCKCNDCNQKQKHD) was used as the immunogen for this TRPC6 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product TRPC6 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 1-192) antibody
TRPC6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 249-265), (Middle Region) antibodyTRPC6 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB620777 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyTRPC6 适用: 人, Chimpanzee WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3F2-H10-F2 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 24-38), (Intracellular), (N-Term) antibodyTRPC6 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB591644 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB447436 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyVerified TRPC6 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 732-931) antibodyTRPC6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyTRPC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the TRPC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the TRPC6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
- 别名
- TRPC6 (TRPC6 产品)
- 别名
- FSGS2 antibody, TRP6 antibody, AV025995 antibody, LLHWJM002 antibody, LLHWJM003 antibody, LLHWJM004 antibody, TRP-6 antibody, Trrp6 antibody, mtrp6 antibody, trp6 antibody, bZ1P14.9 antibody, si:rp71-1p14.9 antibody, trpc6 antibody, transient receptor potential cation channel subfamily C member 6 antibody, transient receptor potential cation channel, subfamily C, member 6 antibody, transient receptor potential cation channel, subfamily C, member 6a antibody, TRPC6 antibody, Trpc6 antibody, trpc6a antibody, trpc6 antibody
- 背景
- Transient receptor potential cation channel, subfamily C, member 6, also known as TRP6, is a transient receptor potentialion channel. Northern blot analysis revealed that TRPC6 is expressed primarily in placenta, lung, spleen, ovary, and small intestine. The protein is a nonselective cation channel that is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Although TRPC3, the closest structural relative of TRPC6, is activated in the same manner, human TRPC1 and mouse Trpc4 and Trpc5 were unresponsive to DAG. Immunofluorescence studies showed that most TRPC6 expression is confined to podocytes. It is also expressed in glomerular endothelial cells. Cardiac-specific overexpression of the protein in transgenic mice resulted in heightened sensitivity to stress, a propensity for lethal cardiac growth and heart failure, and an increase in Nfat-dependent expression of beta-myosin heavy chain(MYH7), a marker for pathologic hypertrophy. Studies of Trpc6 -/- mice showed that it has a role in regulation of smooth muscle tone in blood vessels and lung.
- UniProt
- Q9Y210
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