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Cytokeratin 18 抗体

KRT18 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal KRT18-834 unconjugated
产品编号 ABIN3026948
发货至: 中国
  • 抗原 See all Cytokeratin 18 (KRT18) 抗体
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    适用
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    宿主
    • 164
    • 122
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    小鼠
    克隆类型
    • 151
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    单克隆
    标记
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    This Cytokeratin 18 antibody is un-conjugated
    应用范围
    • 216
    • 99
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    • 27
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    无交叉反应
    小鼠, 大鼠, 绵羊, Hamster, 牛, 犬, 猪
    产品特性
    This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant full-length human KRT18 protein was used as the immunogen for the Cytokeratin 18 antibody.
    克隆位点
    KRT18-834
    亚型
    IgG1
    Top Product
    Discover our top product KRT18 Primary Antibody
  • 应用备注
    Optimal dilution of the Cytokeratin 18 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Cytokeratin 18 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    别名
    Cytokeratin 18 (KRT18 产品)
    背景
    This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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