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CLEC4E 抗体 (C-Term)

CLEC4E 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3024557
发货至: 中国
  • 抗原 See all CLEC4E 抗体
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    抗原表位
    • 16
    • 7
    • 3
    • 1
    • 1
    C-Term
    适用
    人, 大鼠, 小鼠
    宿主
    • 24
    • 6
    克隆类型
    • 25
    • 5
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC4E antibody is un-conjugated
    应用范围
    • 25
    • 16
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A affinity chromatography
    免疫原
    A recombinant protein fragment from the C-terminal portion of human CLEC4E was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product CLEC4E Primary Antibody
  • 应用备注
    Provided assay concentrations are suggestions only, CLEC4E antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the CLEC4E antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    别名
    CLEC4E (CLEC4E 产品)
    别名
    CLECSF9 antibody, MINCLE antibody, C86253 antibody, Clecsf9 antibody, Mincle antibody, CLEC4E antibody, C-type lectin domain family 4 member E antibody, C-type lectin domain family 4, member e antibody, C-type lectin domain family 4, member E antibody, CLEC4E antibody, Clec4e antibody, LOC611538 antibody
    背景
    CLEC4 is a member of the C-type lectin family of proteins that plays a role in inflammatory and immune response. CLEC4E, also called Mincle (Macrophage-inducible C-type lectin), is found on the surface of activated macrophages and phagocytes. It is a receptor for both non-self (fungi and mycobacteria), and self (damaged cells) ligands. Dead cells release SAP130 (Sin3A-Associated Protein, 130  kDa), a small nuclear ribonucleoprotein component. CLEC4E senses this and interacts with the ITAM-containing adaptor protein FcRgamma, and via Syk and CARD9 signaling, activates the production of inflammatory cytokines such as TNFa, MIP-2 and IL-6.
    基因ID
    26253
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