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NR1H3 抗体 (AA 50-330)

NR1H3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3023023
发货至: 中国
  • 抗原 See all NR1H3 抗体
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    抗原表位
    • 16
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-330
    适用
    • 75
    • 56
    • 45
    • 17
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 83
    • 9
    • 2
    克隆类型
    • 77
    • 17
    多克隆
    标记
    • 42
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NR1H3 antibody is un-conjugated
    应用范围
    • 80
    • 31
    • 27
    • 27
    • 27
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    AGGTAGVGLE AAEPTALLTR AEPPSEPTEI RPQKRKKGPA PKMLGNELCS VCGDKASGFH YNVLSCEGCK GFFRRSVIKG AHYICHSGGH CPMDTYMRRK CQECRLRKCR QAGMREECVL SEEQIRLKKL KRQEEEQAHA TSLPPRASSP PQILPQLSPE QLGMIEKLVA AQQQCNRRSF SDRLRVTPWP MAPDPHSREA RQQRFAHFTE LAIVSVQEIV DFAKQLPGFL QLSREDQIAL LKTSAIEVML LETSRRYNPG SESITFLKDF SYNREDFAKA G
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human LXRalpha (NP_005684.2).
    亚型
    IgG
    Top Product
    Discover our top product NR1H3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Qian, Ma, Wu, Yu, Lin, Ying, Wen, Gao: "G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).

  • 抗原
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    别名
    NR1H3 (NR1H3 产品)
    别名
    NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
    背景
    The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,NR1H3,LXR-a,LXRA,RLD-1,LXR alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,NR1H3
    分子量
    43 kDa/45 kDa/50 kDa
    基因ID
    10062
    UniProt
    Q13133
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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