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- 抗原 See all NR1H3 抗体
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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抗原表位
- AA 50-330
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1H3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AGGTAGVGLE AAEPTALLTR AEPPSEPTEI RPQKRKKGPA PKMLGNELCS VCGDKASGFH YNVLSCEGCK GFFRRSVIKG AHYICHSGGH CPMDTYMRRK CQECRLRKCR QAGMREECVL SEEQIRLKKL KRQEEEQAHA TSLPPRASSP PQILPQLSPE QLGMIEKLVA AQQQCNRRSF SDRLRVTPWP MAPDPHSREA RQQRFAHFTE LAIVSVQEIV DFAKQLPGFL QLSREDQIAL LKTSAIEVML LETSRRYNPG SESITFLKDF SYNREDFAKA G
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human LXRalpha (NP_005684.2).
- 亚型
- IgG
- Top Product
- Discover our top product NR1H3 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).
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G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).
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- 抗原
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- 别名
- NR1H3 (NR1H3 产品)
- 别名
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- 背景
- The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,NR1H3,LXR-a,LXRA,RLD-1,LXR alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,NR1H3
- 分子量
- 43 kDa/45 kDa/50 kDa
- 基因ID
- 10062
- UniProt
- Q13133
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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