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DNMT3A 抗体 (AA 500-700)

DNMT3A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022834
发货至: 中国
  • 抗原 See all DNMT3A 抗体
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    抗原表位
    • 16
    • 16
    • 13
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-700
    适用
    • 128
    • 50
    • 48
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 119
    • 12
    克隆类型
    • 109
    • 22
    多克隆
    标记
    • 58
    • 11
    • 10
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This DNMT3A antibody is un-conjugated
    应用范围
    • 101
    • 63
    • 30
    • 27
    • 26
    • 16
    • 12
    • 12
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    序列
    SVTQKHIQEW GPFDLVIGGS PCNDLSIVNP ARKGLYEGTG RLFFEFYRLL HDARPKEGDD RPFFWLFENV VAMGVSDKRD ISRFLESNPV MIDAKEVSAA HRARYFWGNL PGMNRPLAST VNDKLELQEC LEHGRIAKFS KVRTITTRSN SIKQGKDQHF PVFMNEKEDI LWCTEMERVF GFPVHYTDVS NMSRLARQRL L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human DNMT3A (NP_715640.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

    Xi, Gao, Yang, Ye, Zhang, Wu, Jiang, Zhang: "Anticancer drugs induce hypomethylation of the acetylcholinesterase promoter via a phosphorylated-p38-DNMT1-AChE pathway in apoptotic hepatocellular carcinoma cells." in: The international journal of biochemistry & cell biology, Vol. 68, pp. 21-32, (2016) (PubMed).

    Zeng, Huang, Wang, Wu, Wu, Huang: "Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells." in: Neuroscience, Vol. 294, pp. 172-81, (2015) (PubMed).

  • 抗原
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    别名
    DNMT3A (DNMT3A 产品)
    别名
    DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
    背景
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.,DNMT3A,DNMT3A2,M.HsaIIIA,TBRS,DNMT3A,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA methylation,DNMT3A
    分子量
    16 kDa/81 kDa/101 kDa
    基因ID
    1788
    UniProt
    Q9Y6K1
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