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ABCG8 抗体 (AA 1-320)

ABCG8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022643
发货至: 中国
  • 抗原 See all ABCG8 抗体
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    抗原表位
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-320
    适用
    • 21
    • 14
    • 13
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCG8 antibody is un-conjugated
    应用范围
    • 15
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MAGKAAEERG LPKGATPQDT SGLQDRLFSS ESDNSLYFTY SGQPNTLEVR DLNYQVDLAS QVPWFEQLAQ FKMPWTSPSC QNSCELGIQN LSFKVRSGQM LAIIGSSGCG RASLLDVITG RGHGGKIKSG QIWINGQPSS PQLVRKCVAH VRQHNQLLPN LTVRETLAFI AQMRLPRTFS QAQRDKRVED VIAELRLRQC ADTRVGNMYV RGLSGGERRR VSIGVQLLWN PGILILDEPT SGLDSFTAHN LVKTLSRLAK GNRLVLISLH QPRSDIFRLF DLVLLMTSGT PIYLGAAQHM VQYFTAIGYP CPRYSNPADF
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human ABCG8 (NP_071882.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Wu: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." in: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).

  • 抗原
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    别名
    ABCG8 (ABCG8 产品)
    别名
    DDBDRAFT_0167690 antibody, DDBDRAFT_0191232 antibody, DDB_0167690 antibody, DDB_0191232 antibody, zgc:172358 antibody, GBD4 antibody, STSL antibody, 1300003C16Rik antibody, AI114946 antibody, sterolin-2 antibody, ATP binding cassette subfamily G member 8 antibody, ATP-binding cassette sub-family G member 8 antibody, ABC transporter G family protein antibody, ATP-binding cassette, sub-family G (WHITE), member 8 antibody, ABCG8 antibody, PTRG_02054 antibody, abcG8 antibody, abcg8 antibody, Abcg8 antibody
    背景
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.,ABCG8,GBD4,STSL,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,ABCG8
    分子量
    75 kDa
    基因ID
    64241
    UniProt
    Q9H221
    途径
    Lipid Metabolism
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