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BTRC 抗体 (AA 50-340)

BTRC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022334
发货至: 中国
  • 抗原 See all BTRC 抗体
    BTRC (beta-Transducin Repeat Containing (BTRC))
    抗原表位
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 50-340
    适用
    • 44
    • 16
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 43
    • 5
    克隆类型
    • 43
    • 5
    多克隆
    标记
    • 21
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BTRC antibody is un-conjugated
    应用范围
    • 28
    • 24
    • 19
    • 16
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    AFQNSSERED CNNGEPPRKI IPEKNSLRQT YNSCARLCLN QETVCLASTA MKTENCVAKT KLANGTSSMI VPKQRKLSAS YEKEKELCVK YFEQWSESDQ VEFVEHLISQ MCHYQHGHIN SYLKPMLQRD FITALPARGL DHIAENILSY LDAKSLCAAE LVCKEWYRVT SDGMLWKKLI ERMVRTDSLW RGLAERRGWG QYLFKNKPPD GNAPPNSFYR ALYPKIIQDI ETIESNWRCG RHSLQRIHCR SETSKGVYCL QYDDQKIVSG LRDNTIKIWD KNTLECKRIL T
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 50-340 of human beta-TrCP/BTRC (NP_378663.1).
    亚型
    IgG
    Top Product
    Discover our top product BTRC Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BTRC (beta-Transducin Repeat Containing (BTRC))
    别名
    BTRC (BTRC 产品)
    别名
    BTRC antibody, Beta-TrCP antibody, betaTrCP antibody, btrcp antibody, btrcp1 antibody, fbw1a antibody, fbxw1 antibody, fbxw1a antibody, fwd1 antibody, btrc antibody, beta-TrCP antibody, BETA-TRCP antibody, FBW1A antibody, FBXW1 antibody, FBXW1A antibody, FWD1 antibody, bTrCP antibody, bTrCP1 antibody, beta-TrCP1 antibody, btrc-a antibody, Beta-Trcp1 antibody, Fbw1a antibody, HOS antibody, Slimb antibody, b-TrCP antibody, mKIAA4123 antibody, beta-transducin repeat containing E3 ubiquitin protein ligase antibody, beta-transducin repeat containing antibody, beta-TrCP antibody, beta-transducin repeat containing E3 ubiquitin protein ligase S homeolog antibody, beta-transducin repeat containing protein antibody, BTRC antibody, btrc antibody, LOC100634006 antibody, Btrc antibody, btrc.S antibody
    背景
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.,BTRC,BETA-TRCP,FBW1A,FBXW1,FBXW1A,FWD1,bTrCP,bTrCP1,betaTrCP,Beta-TRCP,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Hedgehog Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,BTRC
    分子量
    65 kDa/68 kDa
    基因ID
    8945
    UniProt
    Q9Y297
    途径
    Cell Division Cycle, Hedgehog Signaling
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