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RASA1 抗体 (AA 140-220)

RASA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022298
发货至: 中国
  • 抗原 See all RASA1 抗体
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    抗原表位
    • 15
    • 15
    • 13
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-220
    适用
    • 48
    • 29
    • 28
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 71
    • 7
    • 1
    克隆类型
    • 73
    • 6
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RASA1 antibody is un-conjugated
    应用范围
    • 36
    • 32
    • 26
    • 26
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    PPYLPPLGAG LGTVDEGDSL DGPEYEEEEV AIPLTAPPTN QWYHGKLDRT IAEERLRQAG KSGSYLIRES DRRPGSFVLS F
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human RASA1 (NP_002881.1).
    亚型
    IgG
    Top Product
    Discover our top product RASA1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    别名
    RASA1 (RASA1 产品)
    别名
    CG9209 antibody, D-RasGAP antibody, Dmel\\CG9209 antibody, RAS-GAP antibody, RasGAP antibody, RasGap antibody, rasGap antibody, CM-AVM antibody, CMAVM antibody, GAP antibody, PKWS antibody, RASA antibody, RASGAP antibody, p120GAP antibody, p120RASGAP antibody, GAPX antibody, Rasa antibody, Gap antibody, vacuolar peduncle antibody, RAS p21 protein activator 1 antibody, vap antibody, RASA1 antibody, Rasa1 antibody
    背景
    The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.,RASA1,CM-AVM,CMAVM,GAP,PKWS,RASA,RASGAP,p120,p120GAP,p120RASGAP,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RASA1
    分子量
    58 kDa/100 kDa/101 kDa/116 kDa
    基因ID
    5921
    UniProt
    P20936
    途径
    Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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