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BDNF 抗体 (AA 20-247)

Name: BDNF 抗体 (AA 20-247)
Brand: antibodies-online
SKU: ABIN3021893
Availability: OutOfStock

BDNF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-247) antibody (ABIN3021893)

Western blot analysis of extracts of various cell lines, using BDNF antibody.

Immunofluorescence analysis of U2OS cells using BDNF antibody.

3 images

(3 references)

产品编号 ABIN3021893

发货至: 中国

Datasheet as PDF

抗原 See all BDNF 抗体

BDNF (Brain-Derived Neurotrophic Factor (BDNF))
抗原表位
16

16

11

10

8

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 20-247
适用
115

58

56

14

10

10

9

6

5

5

5

4

3

3

1
人
宿主
110

25

4

3

2

2
兔
Compatible Secondaries
克隆类型
115

30
多克隆
标记
83

17

10

5

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This BDNF antibody is un-conjugated
应用范围
114

49

48

31

26

24

18

13

13

12

9

6

3

2

2

1

1

1

1
Western Blotting (WB)

序列

PMKEANIRGQ GGLAYPGVRT HGTLESVNGP KAGSRGLTSL ADTFEHVIEE LLDEDQKVRP NEENNKDADL YTSRVMLSSQ VPLEPPLLFL LEEYKNYLDA ANMSMRVRRH SDPARRGELS VCDSISEWVT AADKKTAVDM SGGTVTVLEK VPVSKGQLKQ YFYETKCNPM GYTKEGCRGI DKRHWNSQCR TTQSYVRALT MDSKKRIGWR FIRIDTSCVC TLTIKRGR

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 20-247 of human BDNF (NP_733928.1).

亚型

IgG

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anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody
BDNF 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3D9C5 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 151-247) antibody
BDNF 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) antibody
BDNF 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (Internal Region) antibody
Verified BDNF 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibody
BDNF 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236) antibody
BDNF 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibody
BDNF 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236), (C-Term) antibody
BDNF 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14839 unconjugated

应用备注

WB,1:500 - 1:2000

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Sidler, Aitken, Jiang, Sotiropoulos, Aggarwal, Anees, Chong, Siebenaller, Thanabalasingam, White, Choufani, Weksberg, Sangiorgi, Wrana, Delgado-Olguin, Bägli et al.: "DNA Methylation Reduces the Yes-Associated Protein 1/WW Domain Containing Transcription Regulator 1 Pathway and Prevents Pathologic Remodeling during Bladder Obstruction by Limiting Expression of ..." in: The American journal of pathology, Vol. 188, Issue 10, pp. 2177-2194, (2018) (PubMed).

Hang, Zhao, Sun, Li, Han, Du, Li: "Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats." in: Journal of cellular and molecular medicine, Vol. 21, Issue 4, pp. 685-696, (2017) (PubMed).

Hang, Sun, Guo, Zhao, Du: "BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats." in: International journal of biological sciences, Vol. 12, Issue 8, pp. 979-89, (2017) (PubMed).
抗原

BDNF (Brain-Derived Neurotrophic Factor (BDNF))

别名

BDNF (BDNF 产品)

背景

This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.,BDNF,ANON2,BULN2,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,BDNF

分子量

27 kDa/28 kDa/29 kDa/31 kDa/37 kDa

基因ID

627

UniProt

P23560

途径

RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity