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TPMT 抗体 (AA 1-245)

TPMT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021279
发货至: 中国
  • 抗原 See all TPMT 抗体
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-245
    适用
    • 33
    • 12
    • 11
    • 2
    • 2
    宿主
    • 28
    • 5
    克隆类型
    • 27
    • 6
    多克隆
    标记
    • 19
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPMT antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MDGTRTSLDI EEYSDTEVQK NQVLTLEEWQ DKWVNGKTAF HQEQGHQLLK KHLDTFLKGK SGLRVFFPLC GKAVEMKWFA DRGHSVVGVE ISELGIQEFF TEQNLSYSEE PITEIPGTKV FKSSSGNISL YCCSIFDLPR TNIGKFDMIW DRGALVAINP GDRKCYADTM FSLLGKKFQY LLCVLSYDPT KHPGPPFYVP HAEIERLFGK ICNIRCLEKV DAFEERHKSW GIDCLFEKLY LLTEK
    交叉反应
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPMT (NP_000358.1).
    亚型
    IgG
    Top Product
    Discover our top product TPMT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:10 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    别名
    TPMT (TPMT 产品)
    别名
    MGC84277 antibody, AW106912 antibody, NHLRC1 antibody, thiopurine S-methyltransferase L homeolog antibody, thiopurine S-methyltransferase, tandem duplicate 2 antibody, thiopurine S-methyltransferase TpmT antibody, thiopurine S-methyltransferase antibody, Thiopurine S-methyltransferase antibody, thiopurine methyltransferase antibody, tpmt.L antibody, tpmt.2 antibody, tpmT antibody, MCA0794 antibody, Pnap_4948 antibody, Hhal_1383 antibody, TK90_1044 antibody, Slit_1144 antibody, Tint_0842 antibody, Fbal_3334 antibody, Celly_3188 antibody, Weevi_1737 antibody, Psefu_2696 antibody, Metme_3860 antibody, Tpmt antibody, TPMT antibody
    背景
    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT
    分子量
    28 kDa
    基因ID
    7172
    UniProt
    P51580
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