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TRAF6 抗体 (AA 263-522)

TRAF6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021194
发货至: 中国
  • 抗原 See all TRAF6 抗体
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    抗原表位
    • 15
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-522
    适用
    • 57
    • 31
    • 26
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 56
    • 4
    • 2
    克隆类型
    • 54
    • 8
    多克隆
    标记
    • 39
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAF6 antibody is un-conjugated
    应用范围
    • 58
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    QENTQSHMRM LAQAVHSLSV IPDSGYISEV RNFQETIHQL EGRLVRQDHQ IRELTAKMET QSMYVSELKR TIRTLEDKVA EIEAQQCNGI YIWKIGNFGM HLKCQEEEKP VVIHSPGFYT GKPGYKLCMR LHLQLPTAQR CANYISLFVH TMQGEYDSHL PWPFQGTIRL TILDQSEAPV RQNHEEIMDA KPELLAFQRP TIPRNPKGFG YVTFMHLEAL RQRTFIKDDT LLVRCEVSTR FDMGSLRREG FQPRSTDAGV
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human TRAF6 (NP_004611.1).
    亚型
    IgG
    Top Product
    Discover our top product TRAF6 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Teng, Luo, Yu, Chen, Huang, Chen, Xie, Zeng, Luo, Xiong, Liu, Hou, Feng: "CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells." in: Genes and immunity, (2018) (PubMed).

  • 抗原
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    别名
    TRAF6 (TRAF6 产品)
    别名
    MGC:3310 antibody, RNF85 antibody, 2310003F17Rik antibody, AI851288 antibody, C630032O20Rik antibody, rnf85 antibody, traf6 antibody, xtraf6 antibody, CG10961 antibody, DTRAF2 antibody, Dmel\\CG10961 antibody, TRAF antibody, TRAF2 antibody, TRAF6 antibody, Traf2 antibody, dTRAF2 antibody, dTRAF6 antibody, dTraf2 antibody, dtraf2 antibody, GB10539 antibody, fi15f02 antibody, wu:fi15f02 antibody, zgc:63704 antibody, TNF receptor associated factor 6 antibody, TNF receptor-associated factor 6 antibody, TNF receptor associated factor 6 L homeolog antibody, TNF-receptor-associated factor 6 antibody, TNF receptor associated factor 6 S homeolog antibody, TRAF6 antibody, Traf6 antibody, traf6.L antibody, traf6 antibody, LOC551819 antibody, traf6.S antibody
    背景
    The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.,TRAF6,MGC:3310,RNF85,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Death receptors & ligands,Growth factor,TNF,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TRAF6
    分子量
    59 kDa
    基因ID
    7189
    UniProt
    Q9Y4K3
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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