我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Caspase 1 抗体 (AA 1-311)

Name: Caspase 1 抗体 (AA 1-311)
Brand: antibodies-online
SKU: ABIN3021171
Availability: OutOfStock

CASP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using CASP1 antibody.

Immunofluorescence analysis of MCF7 cells using Caspase-1 Rabbit pAb (ABIN3021170, ABIN3021171, ABIN3021172 and ABIN6214049) at dilution of 1:150 (40x lens).

Immunohistochemistry of paraffin-embedded human colon using Caspase-1 Rabbit pAb (ABIN3021170, ABIN3021171, ABIN3021172 and ABIN6214049) at dilution of 1:100 (40x lens).

IHC

Immunoprecipitation analysis of 200 μg extracts of THP-1 cells, using 3 μg Caspase-1 antibody (ABIN3021170, ABIN3021171, ABIN3021172 and ABIN6214049).

Confocal immunofluorescence analysis of Raw264.

5 images

(2 references)

产品编号 ABIN3021171

发货至: 中国

Datasheet as PDF

抗原 See all Caspase 1 (CASP1) 抗体

Caspase 1 (CASP1)
抗原表位
8

7

7

7

4

4

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-311
适用
93

35

29

5

2

1

1

1

1

1

1
人
宿主
103

11

3

1
兔
Compatible Secondaries
克隆类型
94

24
多克隆
标记
79

18

7

3

2

2

2

2

2

2
This Caspase 1 antibody is un-conjugated
应用范围
90

46

45

24

13

13

11

6

3

3

3

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

序列

MADKVLKEKR KLFIRSMGEA PQAVQDNPAM PTSSGSEGNV KLCSLEEAQR IWKQKSAEIY PIMDKSSRTR LALIICNEEF DSIPRRTGAE VDITGMTMLL QNLGYSVDVK KNLTASDMTT ELEAFAHRPE HKTSDSTFLV FMSHGIREGI CGKKHSEQVP DILQLNAIFN MLNTKNCPSL KDKPKVIIIQ ACRGDSPGVV WFKDSVGVSG NLSLPTTEEF EDDAIKKAHI EKDFIAFCSS TPDNVSWRHP TMGSVFIGRL IEHMQEYACS CDVEEIFRKV RFSFEQPDGR AQMPTTERVT LTRCFYLFPG H

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-311 of human Caspase-1 (NP_150635.1).

亚型

IgG

Top Product

Discover our top product CASP1 Primary Antibody
anti-Caspase 1 (CASP1) (AA 317-404) antibody
CASP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 120-297) antibody
CASP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 119-296) antibody
CASP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 120-297) antibody
CASP1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 1-100) antibody
CASP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D2 unconjugated

anti-Caspase 1 (CASP1) antibody
CASP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 130-210), (Cleaved-Asp210) antibody
CASP1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 120-269) antibody
CASP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (AA 120-269) antibody
CASP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Caspase 1 (CASP1) (Cleaved-Asp210) antibody
CASP1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Dinesh, Rasool et al.: "Berberine, an isoquinoline alkaloid suppresses TXNIP mediated NLRP3 inflammasome activation in MSU crystal stimulated RAW 264.7 macrophages through the upregulation of Nrf2 transcription factor and ..." in: International immunopharmacology, Vol. 44, pp. 26-37, (2017) (PubMed).

Ma, Wang, Wang, Tian, Kang, Liu, Wang, Dou, Zhou: "Effective antimicrobial activity of Cbf-14, derived from a cathelin-like domain, against penicillin-resistant bacteria." in: Biomaterials, Vol. 87, pp. 32-45, (2016) (PubMed).
抗原

Caspase 1 (CASP1)

别名

CASP1 (CASP1 产品)

别名

ICE antibody, IL1BC antibody, P45 antibody, Il1bc antibody, Ice antibody, CASP1 antibody, CG5370 antibody, DCP-1 antibody, DCP1 antibody, Dcp1 antibody, Dmel\\CG5370 antibody, ccp1 antibody, dcp-1 antibody, dcp1 antibody, l(2)01862 antibody, l(2)02132 antibody, caspase 1 antibody, caspase 1, apoptosis-related cysteine peptidase antibody, caspase 4, apoptosis-related cysteine peptidase antibody, Death caspase-1 antibody, caspase-1 antibody, caspase antibody, caspase recruitment domain-containing protein 16 antibody, caspase 4 antibody, CASP1 antibody, Casp1 antibody, CASP4 antibody, Dcp-1 antibody, Caspase1 antibody, LOC5564196 antibody, LOC451519 antibody

背景

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.,CASP1,ICE,IL1BC,P45,caspase-1,Caspase 1,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,CASP1

分子量

10 kDa/29 kDa/35 kDa/42 kDa/45 kDa

基因ID

834

UniProt

P29466

途径

Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome